Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385505 | 0.87 | ESR1 (0.46) | MAOASLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL20385424 | 0.87 | ESR1 (0.46) | MAOASLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL14032656 | 0.86 | ESR1 (0.66) | SLC6A2TAAR1SIGMAR1ESR1ESR2 | |
| SCHEMBL25979412 | 0.83 | CYP2C19 (0.45) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL18950253 | 0.82 | SLC6A2 (0.42) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL24337020 | 0.78 | ESR1 (0.36) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL27813115 | 0.78 | SLC6A2 (0.48) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL27946805 | 0.78 | SLC6A2 (0.48) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL13862942 | 0.78 | KCNA5 (0.52) | SLC6A2SLC6A4SLC6A3TSHRCYP1A2 | |
| SCHEMBL13638230 | 0.78 | KCNA5 (0.52) | SLC6A2SLC6A4SLC6A3TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102066337-A | 5-hydroxypyrimidine-4-carboxamide compounds | DAIICHI SANKYO CO LTD | 2011-05-18 | — | — | CN | disclosed |
| US-20100204160-A1 | SUBSTITUTED 1,2-ETHYLENEDIAMINES, METHODS FOR PREPARING THEM AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-08-12 | — | — | US | disclosed |
| US-7678847-B2 | Encapsulated structural adhesive | APPLETON PAPERS INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20080027060-A1 | DIPEPTIDE NITRILES | ALTMANN EVA | 2008-01-31 | — | — | US | disclosed |
| US-20080027060-A1 | DIPEPTIDE NITRILES | ALTMANN EVA | 2008-01-31 | — | — | US | disclosed |
| US-20070021533-A1 | Encapsulated structural adhesive | APPLETON PAPERS INC. (US) | 2007-01-25 | — | — | US | disclosed |
| US-5519037-A | N-cyanoamidine derivatives as anti-influenza agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-21 | — | — | US | disclosed |
| US-5475012-A | Antiviral against influenza A | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-12-12 | — | — | US | disclosed |
| US-5380734-A | N-cyanoamidine derivatives as anti-influenza agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204160-A1 | SUBSTITUTED 1,2-ETHYLENEDIAMINES, METHODS FOR PREPARING THEM AND USES THEREOF | PSEN1, PSEN2, BACE1 | MAOA 21/4885SLC6A2 192/4885TAAR1 277/4885 |
| US-20080027060-A1 | DIPEPTIDE NITRILES | CTSL, CTSS, CTSB | MAOA 3705/4885SLC6A2 2485/4885TAAR1 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.