Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 14/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065030 | 0.83 | FFAR3 (0.68) | FFAR3ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL5067774 | 0.82 | FFAR3 (1.00) | FFAR3KDM4E | |
| SCHEMBL3242208 | 0.80 | FFAR3 (0.70) | FFAR3ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL13998205 | 0.76 | FFAR3 (0.73) | FFAR3ALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL3249509 | 0.73 | KDM4E (0.61) | FFAR3ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL15859398 | 0.72 | FFAR3 (0.75) | FFAR3KDM4E | |
| SCHEMBL2992233 | 0.71 | SMN1; SMN2 (0.77) | FFAR3ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL3004053 | 0.70 | HSD17B10 (0.66) | FFAR3ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL3329777 | 0.69 | ALDH1A1 (0.78) | FFAR3ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL16211041 | 0.69 | SMN1; SMN2 (0.73) | FFAR3ALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002483-A1 | OPTIONALLY CONDENSED DIHYDRO PYRIDINE, DIHYDROPYRIMIDINE AND DIHYDRO PYRANE DERIVATIVES ACTING AS LATE SODIUM CHANNEL BLOCKERS | CV THERAPEUTICS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| WO-2009006580-A1 | OPTIONALLY CONDENSED DIHYDROPYRIDINE, DIHYDROPYRIMIDINE AND DIHYDROPYRANE DERIVATIVES ACTING AS LATE SODIUM CHANNEL BLOCKERS | CV THERAPEUTICS, INC. (US) | 2009-01-08 | — | — | WO | disclosed |