Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of 2-Allylphenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Allylphenol SCHEMBL16592915 | 1.00 | GABRA1 (0.48) | GABRA1GABRB2POLBAKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL11759401 | 0.93 | GABRA1 (0.43) | GABRA1GABRB2POLBAKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL27330284 | 0.93 | GABRA1 (0.46) | GABRA1GABRB2POLBAKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL28264867 | 0.90 | GABRA1 (0.41) | GABRA1GABRB2POLBAKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL88373 | 0.90 | GABRA1 (0.53) | GABRA1GABRB2POLBAKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL5489147 | 0.90 | GABRA1 (0.57) | GABRA1GABRB2POLBAKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL160157 | 0.90 | GABRA1 (0.57) | GABRA1GABRB2POLBAKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL31591833 | 0.90 | GABRA1 (0.57) | GABRA1GABRB2POLBAKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL29381085 | 0.90 | GABRA1 (0.57) | GABRA1GABRB2POLBAKR1B1HSPA5 | |
| 2-Allylphenol SCHEMBL732760 | 0.89 | GABRA1 (0.48) | GABRA1GABRB2POLBAKR1B1HSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146479-A2 | POLYMER AND POLYMER EMULSION, PREPARATION METHOD THEREFOR, CEMENT SLURRY, AND APPLICATION OF POLYMER AND POLYMER EMULSION | 中国石油化工股份有限公司 | 2024-07-11 | — | — | WO | claimed |
| CN-117717086-A | Stable cymoxanil pesticide composition | 龙灯农业化工国际有限公司 | 2024-03-19 | — | — | CN | claimed |
| US-11639457-B2 | Heat transfer fluids and methods for preventing corrosion in heat transfer systems | PRESTONE PRODUCTS CORPORATION (US) | 2023-05-02 | — | — | US | claimed |
| CN-115819642-A | Allyl ether sulfate polymerizable surfactants and methods of use | 罗地亚经营管理公司 | 2023-03-21 | — | — | CN | claimed |
| CN-112794951-B | Manufacturing process of high-weather-resistance ASA special for PVC resin tiles | 山东宏福化学有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-114231133-A | Water-based metal antirust paint | 广东家实多集团有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-114096586-A | Polymerizable surfactants having resistance to water whitening and methods of use thereof | 罗地亚经营管理公司 | 2022-02-25 | — | — | CN | claimed |
| EP-3648607-A1 | PESTICIDE COMPOSITIONS | Rhodia Operations (FR) | 2020-05-13 | — | — | EP | claimed |
| US-20200128831-A1 | Pesticide Compositions | SPECIALTY OPERATIONS FRANCE (FR) | 2020-04-30 | — | — | US | claimed |
| CN-109852188-A | A kind of flexible corrosion protection acroleic acid polyurethane lotion and preparation method thereof | 常熟巴德富科技有限公司 | 2019-06-07 | — | — | CN | claimed |
| US-6277910-B1 | OBTAINED BY MIXING AN AQUEOUS DISPERSION A OF A POLYMER OF GIVEN DRY SOLIDS CONTENT, SURFACTANT(S) AND EMULSIFIABLE RESIN(S) WHICH IS ADDED TO DISPERSION A UNDER AGITATION; HIGH SOLIDS CONTENT; USE AS PAINT OR LACQUER | AKZO NOBEL INDUSTRIAL COATINGS, AB (SE) | 2001-08-21 | — | — | US | claimed |
| EP-0874875-B1 | WATER-BORNE HYBRID BINDER COMPOSITION AND USE THEREOF | AKZO NOBEL IND COATINGS AB (SE) | 2001-06-13 | — | — | EP | claimed |
| WO-2000058228-A1 | RUST AND SCALE REMOVAL COMPOSITION AND PROCESS | CALGON CORPORATION (US) | 2000-10-05 | — | — | WO | claimed |
| EP-0874875-A1 | WATER-BORNE HYBRID BINDER COMPOSITION AND USE THEREOF | Akzo Nobel Industrial Coatings AB (SE) | 1998-11-04 | — | — | EP | claimed |
| WO-1997026303-A1 | WATER-BORNE HYBRID BINDER COMPOSITION AND USE THEREOF | AKZO NOBEL INDUSTRIAL COATINGS AB (SE) | 1997-07-24 | — | — | WO | claimed |
| CN-1127981-A | Aqueous endosulphane suspension concentrates | HOECHST SCHERING AGREVO GMBH (DE) | 1996-07-31 | — | — | CN | claimed |
| US-5520251-A | Method for acidizing oil producing formations | TEXACO INC. (US) | 1996-05-28 | — | — | US | claimed |
| EP-0505935-A1 | Ph controlled antimicrobial formulation | Becton, Dickinson and Company (US) | 1992-09-30 | — | — | EP | claimed |
| US-4853026-A | AQUEOUS SOLUTION OF A SALT OF GLUFOSINATE AND GLYPHOSATE, ORGANIC SOLUTION OF AN ACTIVE HERBICIDE AND A SURFACTANT MIXTURE | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-01 | — | — | US | claimed |
| US-4270917-A | PHOSPHATED ALKYLPHENOL ETHOXYLATE AS CRYSTAL GROWTH INHIBITOR | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-06-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200128831-A1 | Pesticide Compositions | DDT, SGMS2, SGMS1 | GABRA1 598/4885GABRB2 234/4885POLB 3905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.