Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.42 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249160 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL4866268 | 0.86 | KAT6A (0.46) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL3247111 | 0.86 | FLT1 (0.48) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL3253246 | 0.85 | MEP1B (0.48) | ALDH1A1MAPTMEP1BGAALMNA | |
| SCHEMBL3255473 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL3255565 | 0.83 | MEP1B (0.55) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL4869124 | 0.83 | GAA (0.44) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL4871474 | 0.83 | FLT1 (0.52) | ALDH1A1RECQLMEN1KMT2AMAPT | |
| SCHEMBL4860809 | 0.82 | L3MBTL1 (0.46) | ALDH1A1MEN1KMT2AMAPTTP53 | |
| SCHEMBL3251190 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776347-B1 | SULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2010-05-26 | — | — | EP | disclosed |
| US-7396958-B2 | Sulphonamide derivatives, their preparation and their therapeutic application | SANOFI AVENTIS (FR) | 2008-07-08 | — | — | US | disclosed |
| US-20070185136-A1 | SULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI-AVENTIS (FR) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185136-A1 | SULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | HCRTR2, GIPR, SSTR2 | ALDH1A1 2179/4885RECQL 2322/4885PPARG 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.