SCHEMBL3254036

SCHEMBL3254036

Clc1cccnc1-n1nc(Br)cc1Br

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.39
CYP17A1 P05093 1/20 0.35
CYP1A2 P05177 1/20 0.35
TRPV1 Q8NER1 3/20 0.34
HSD11B1 P28845 2/20 0.33
OPRL1 P41146 3/20 0.33
KCNH2 Q12809 3/20 0.33
TRPA1 O75762 1/20 0.33
BACE1 P56817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30658613 1.00 DHODH (0.39) DHODHCYP17A1CYP1A2TRPV1HSD11B1
SCHEMBL23249649 0.98 DHODH (0.38) DHODHCYP17A1CYP1A2TRPV1HSD11B1
Magnesium SCHEMBL29514747 0.98 DHODH (0.38) DHODHCYP17A1CYP1A2TRPV1HSD11B1
SCHEMBL28411296 0.84 DHODH (0.38) DHODHCYP17A1CYP1A2TRPV1HSD11B1
SCHEMBL29101572 0.84 DHODH (0.38) DHODHCYP17A1CYP1A2TRPV1HSD11B1
SCHEMBL29437213 0.84 DHODH (0.42) DHODHCYP17A1CYP1A2TRPV1HSD11B1
SCHEMBL29101597 0.84 DHODH (0.40) DHODHCYP17A1CYP1A2TRPV1HSD11B1
SCHEMBL12528202 0.84 DHODH (0.42) DHODHCYP17A1CYP1A2TRPV1HSD11B1
SCHEMBL22315221 0.81 DHODH (0.37) DHODHCYP17A1CYP1A2TRPV1OPRL1
SCHEMBL3418088 0.80 DHODH (0.38) DHODHCYP17A1CYP1A2TRPV1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535388-B Chlorantraniliprole Process for the preparation of amides 江苏七洲绿色科技研究院有限公司 2024-12-10 CN claimed
CN-116535388-A Preparation method of chlorantraniliprole 江苏七洲绿色科技研究院有限公司 2023-08-04 CN claimed
CN-114641471-B Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2025-05-23 CN disclosed
EP-4219455-B1 METHODS FOR THE PREPARATION OF A HALOGENATED PYRAZOLE FMC CORP (US) 2024-12-11 EP disclosed
CN-116535388-B Chlorantraniliprole Process for the preparation of amides 江苏七洲绿色科技研究院有限公司 2024-12-10 CN disclosed
CN-116535388-B Chlorantraniliprole Process for the preparation of amides 江苏七洲绿色科技研究院有限公司 2024-12-10 CN disclosed
CN-119039270-A Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2024-11-29 CN disclosed
US-20240300901-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC IP TECHNOLOGY GMBH (CH) 2024-09-12 US disclosed
CN-114650987-B Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2024-09-06 CN disclosed
US-20240132462-A1 METHOD FOR PREPARING TERT-BUTYL N-((1R,2S,5S)-2-((2-((5-CHLOROPYRIDIN-2-YL)AMINO)-2-OXOACETYL)AMINO)-5-(DIMETHYLCARBAMOYL)CYCLOHEXYL)CARBAMATE FMC IP TECHNOLOGY GMBH (CH) 2024-04-25 US disclosed
EP-4043451-B1 METHODS FOR THE PREPARATION OF AN INTERMEDIATE IN THE SYNTHESIS OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC CORP (US) 2024-02-28 EP disclosed
CN-102746327-A Method for producing hydrazine compound,and production intermediates of hydrazine compound and methods of producing the intermediates SUMITOMO CHEMICAL CO 2012-10-24 CN disclosed
EP-2481724-A1 Method for producing hydrazine compound, and production intermediates of hydrazine compound and methods for producing the intermediates Sumitomo Chemical Company, Limited (JP) 2012-08-01 EP disclosed
EP-2481724-A1 Method for producing hydrazine compound, and production intermediates of hydrazine compound and methods for producing the intermediates Sumitomo Chemical Company, Limited (JP) 2012-08-01 EP disclosed
CN-101784537-A Method for producing hydrazine compound, intermediate for producing hydrazine compound, and method for producing intermediate SUMITOMO CHEMICAL CO 2010-07-21 CN disclosed
US-20100145059-A1 METHOD FOR PRODUCING HYDRAZINE COMPOUND,AND PRODUCTION INTERMEDIATES OF HYDRAZINE COMPOUND AND METHODS OF PRODUCING THE INTERMEDIATES SUMITOMO CHEMICAL COMPANY, LIMITED 2010-06-10 US disclosed
US-20100145059-A1 METHOD FOR PRODUCING HYDRAZINE COMPOUND,AND PRODUCTION INTERMEDIATES OF HYDRAZINE COMPOUND AND METHODS OF PRODUCING THE INTERMEDIATES SUMITOMO CHEMICAL COMPANY, LIMITED 2010-06-10 US disclosed
US-20100145059-A1 METHOD FOR PRODUCING HYDRAZINE COMPOUND,AND PRODUCTION INTERMEDIATES OF HYDRAZINE COMPOUND AND METHODS OF PRODUCING THE INTERMEDIATES SUMITOMO CHEMICAL COMPANY, LIMITED 2010-06-10 US disclosed
EP-2189455-A1 PROCESS FOR PRODUCTION OF HYDRAZINE COMPOUND, INTERMEDIATE FOR PRODUCTION OF HYDRAZINE COMPOUND, AND PROCESS FOR PRODUCTION OF THE INTERMEDIATE Sumitomo Chemical Company, Limited (JP) 2010-05-26 EP disclosed
EP-2189455-A1 PROCESS FOR PRODUCTION OF HYDRAZINE COMPOUND, INTERMEDIATE FOR PRODUCTION OF HYDRAZINE COMPOUND, AND PROCESS FOR PRODUCTION OF THE INTERMEDIATE Sumitomo Chemical Company, Limited (JP) 2010-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145059-A1 METHOD FOR PRODUCING HYDRAZINE COMPOUND,AND PRODUCTION INTERMEDIATES OF HYDRAZINE COMPOUND AND METHODS OF PRODUCING THE INTERMEDIATES HPD, CYP51A1, HAAO DHODH 17/4885CYP17A1 438/4885CYP1A2 83/4885
US-20240300901-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID TUBA3C, KYAT3, AADAC DHODH 410/4885CYP17A1 1696/4885CYP1A2 48/4885
US-20240132462-A1 METHOD FOR PREPARING TERT-BUTYL N-((1R,2S,5S)-2-((2-((5-CHLOROPYRIDIN-2-YL)AMINO)-2-OXOACETYL)AMINO)-5-(DIMETHYLCARBAMOYL)CYCLOHEXYL)CARBAMATE CPS1, TERT, PRMT5 DHODH 939/4885CYP17A1 3623/4885CYP1A2 277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.