Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.59 |
| ▸ | DRD4 | P21917 | 6/20 | 0.59 |
| ▸ | DRD3 | P35462 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18071260 | 0.94 | DRD2 (0.53) | DRD2DRD4DRD3L3MBTL1MEN1 | |
| SCHEMBL1374364 | 0.93 | DRD2 (0.57) | DRD2DRD4DRD3L3MBTL1MEN1 | |
| SCHEMBL18643854 | 0.91 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1MEN1 | |
| SCHEMBL18643855 | 0.91 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1MEN1 | |
| SCHEMBL13572532 | 0.91 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1MEN1 | |
| SCHEMBL8955642 | 0.91 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1MEN1 | |
| SCHEMBL26116498 | 0.91 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1MEN1 | |
| SCHEMBL2806021 | 0.91 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1MEN1 | |
| SCHEMBL13945546 | 0.89 | DRD2 (0.49) | DRD2DRD4DRD3L3MBTL1MEN1 | |
| P-Xylene SCHEMBL6845696 | 0.88 | ALDH1A1 (0.60) | DRD2DRD4DRD3L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088493-A1 | FURO-PYRIDONE COMPOUND AND USE THEREOF | 中国科学院广州生物医药与健康研究院 | 2023-05-25 | — | — | WO | disclosed |
| US-11538992-B2 | Formulation of an organic functional material | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| EP-3532565-B1 | FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL | MERCK PATENT GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |
| US-20200127203-A1 | FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL | MERCK PATENT GMBH (DE) | 2020-04-23 | — | — | US | disclosed |
| WO-2018102725-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | Arvinas, Inc. (US) | 2018-06-07 | — | — | WO | disclosed |
| WO-2018077660-A1 | FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL | MERCK PATENT GMBH (DE) | 2018-05-03 | — | — | WO | disclosed |
| US-9758502-B2 | Dihydropyrone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-09-12 | — | — | US | disclosed |
| EP-2727947-B1 | COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING HARDENED PRODUCT THEREOF | DAINIPPON INK & CHEMICALS (JP) | 2017-03-15 | — | — | EP | disclosed |
| US-9328076-B2 | Molecular glasses with functionalizable groups | HER MAJESTY IN THE RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF DEFENSE (CA) | 2016-05-03 | — | — | US | disclosed |
| US-20150299156-A1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20070082933-A1 | Novel thiazolidin-4-one derivatives | ACTELION PHARMACEUTICALS, LTD. | 2007-04-12 | — | — | US | disclosed |
| US-20070082933-A1 | Novel thiazolidin-4-one derivatives | ACTELION PHARMACEUTICALS, LTD. | 2007-04-12 | — | — | US | disclosed |
| CN-1286865-C | Plastic lens composition plastic lens and process for producing the plastic lens | SHOWA DENKO KK (JP) | 2006-11-29 | — | — | CN | disclosed |
| WO-2006030032-A1 | NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-03-23 | — | — | WO | disclosed |
| WO-2005054215-A1 | 5-(BENZ- (Z) -YLIDENE) -THIAZOLIDIN-4-ONE DERIVATIVES AS IMMUNOSUPPRESSANT AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2005-06-16 | — | — | WO | disclosed |
| US-5147884-A | Microbiocide mixture containing tert-butyl hydroperoxide, a monophenylglycol ether and a diluent; discoloration inhibition, controlling consistency and preventing odor | STERLING DRUG INC. (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0275203-A2 | Heat-sensitive recording material containing color forming components | FUJI PHOTO FILM CO., LTD. (JP) | 1988-07-20 | — | — | EP | disclosed |
| US-4485043-A | Process for producing 1-amino-4-hydroxy-anthraquinones | CIBA-GEIGY AG (CH) | 1984-11-27 | — | — | US | disclosed |
| US-4415494-A | BLUE-TO-BLACK COLORFAST DISPERSE, NITRO DYES; DIAZOTIZING A P-NITROANILINE AND COUPLING WITH AN N-SUBSTITUTED 1-NAPHTHYLAMINE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| EP-0036545-A1 | Water insoluble monoazo dyes, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1981-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299156-A1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | CBR3, DDT, WEE2 | DRD2 855/4885DRD4 748/4885DRD3 821/4885 |
| US-20070082933-A1 | Novel thiazolidin-4-one derivatives | TLR4, IL4, IRF3 | DRD2 2868/4885DRD4 1309/4885DRD3 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.