Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | MLYCD | O95822 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28558959 | 0.93 | MAPT (0.77) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL3061430 | 0.88 | MAPT (1.00) | MAPTHTTGAALMNARAB9A | |
| Hydrochloric Acid SCHEMBL27689202 | 0.86 | MAPT (0.96) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL28277703 | 0.85 | MAPT (0.70) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL27671467 | 0.85 | MAPT (0.86) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL11705109 | 0.85 | TRPV1 (0.82) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL13356363 | 0.85 | MAPT (0.80) | MAPTHTTGAALMNARAB9A | |
| Methyl Alcohol SCHEMBL4593446 | 0.84 | MAPT (0.93) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL15352334 | 0.84 | TP53 (0.67) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL2003074 | 0.83 | MAPT (0.77) | MAPTHTTGAALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110066254-B | Preparation method of isothiazole-3-ketone compound | 温州大学 | 2021-03-19 | — | — | CN | disclosed |
| EP-2099762-B1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-12 | — | — | EP | disclosed |
| US-20100069366-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN-CILAG (NJ) | 2010-03-18 | — | — | US | disclosed |
| EP-2099762-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008068266-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069366-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | NQO2, NDUFB5, NDUFB7 | MAPT 3969/4885HTT 3932/4885GAA 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.