Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144727 | 1.00 | NR3C1 (0.44) | NR3C1CHRNA7TRPA1KMT2AMEN1 | |
| SCHEMBL3144717 | 1.00 | NR3C1 (0.44) | NR3C1CHRNA7TRPA1KMT2AMEN1 | |
| SCHEMBL27086737 | 0.82 | KDM4E (0.45) | TRPA1KMT2AMEN1ALDH1A1ABCB1 | |
| SCHEMBL1741864 | 0.81 | GPR139 (0.40) | TRPA1 | |
| SCHEMBL850878 | 0.80 | NPSR1 (0.49) | KMT2AMEN1ALDH1A1ABCB1ACACB | |
| SCHEMBL30695648 | 0.80 | NPSR1 (0.49) | KMT2AMEN1ALDH1A1ABCB1ACACB | |
| SCHEMBL23200961 | 0.79 | CTSS (0.41) | NR3C1CHRNA7TRPA1KMT2AMEN1 | |
| SCHEMBL18660958 | 0.77 | PPARG (0.43) | TRPA1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL18660808 | 0.77 | PPARG (0.43) | TRPA1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL18660810 | 0.77 | PPARG (0.43) | TRPA1KMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100080786-A1 | Phenyl or Pyridinyl Substituted Indazoles Derivatives | ASTRAZENECA AB (SE) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100080786-A1 | Phenyl or Pyridinyl Substituted Indazoles Derivatives | CYP3A5, CYP3A43, ABCB1 | NR3C1 2328/4885CHRNA7 3736/4885TRPA1 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.