Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249233 | 0.93 | GRIN2B (0.61) | GRIN2BGRIN1 | |
| SCHEMBL3252047 | 0.93 | GRIN1 (0.46) | GRIN2BGRIN1 | |
| SCHEMBL3247035 | 0.89 | GRIN2B (0.47) | GRIN2BGRIN1 | |
| SCHEMBL3242733 | 0.85 | GRIN1 (0.50) | GRIN2BGRIN1 | |
| SCHEMBL3256122 | 0.84 | GRIN2B (0.49) | GRIN2BGRIN1 | |
| SCHEMBL3245322 | 0.82 | GRIN1 (0.51) | GRIN2BGRIN1 | |
| SCHEMBL3252351 | 0.82 | GRIN2B (0.52) | GRIN2BGRIN1 | |
| SCHEMBL3245549 | 0.79 | GRIN1 (0.46) | GRIN2BGRIN1 | |
| SCHEMBL3236751 | 0.79 | GRIN1 (0.46) | GRIN2BGRIN1 | |
| SCHEMBL3247392 | 0.77 | HSD17B3 (0.43) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | claimed |
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |