Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 9/20 | 0.45 |
| ▸ | RAB9A | P51151 | 9/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148021 | 0.88 | KDM4E (0.49) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL3249031 | 0.75 | ALDH1A1 (0.44) | KMT2AL3MBTL1NPC1RAB9ATDP1 | |
| SCHEMBL3256178 | 0.75 | SMN1; SMN2 (0.49) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL3256558 | 0.73 | SRC (0.50) | MCHR1KDM4E | |
| SCHEMBL3256556 | 0.73 | SRC (0.50) | MCHR1KDM4E | |
| SCHEMBL3244126 | 0.72 | KCNH2 (0.49) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL3247108 | 0.69 | MAPT (0.51) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL12610862 | 0.67 | CYP1A2 (0.72) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL12611073 | 0.64 | CYP1A2 (0.63) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL5884420 | 0.64 | MCHR1 (1.00) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001478-B1 | CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-06-02 | — | — | EP | claimed |