Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17394554 | 0.83 | TSHR (0.33) | ALDH1A1TDP1CYP3A4TSHRMEN1 | |
| SCHEMBL28129946 | 0.80 | LTA4H (0.55) | TSHRMAOAMAOBMEN1KMT2A | |
| SCHEMBL1331804 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRMAOA | |
| SCHEMBL2013073 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRMAOA | |
| SCHEMBL202864 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRMAOA | |
| SCHEMBL10576066 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRMAOA | |
| SCHEMBL4455485 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRMAOA | |
| SCHEMBL4446167 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRMAOA | |
| SCHEMBL65211 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRMAOA | |
| SCHEMBL41849 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065310-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | VIA PHARMACEUTICALS, INC (US) | 2010-06-10 | — | — | WO | disclosed |