Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132995 | 0.91 | EGLN3 (0.51) | EGLN3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3127230 | 0.91 | EGLN3 (0.56) | EGLN3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2903353 | 0.90 | ALDH1A1 (0.51) | EGLN3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3252291 | 0.89 | EGLN3 (0.50) | EGLN3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3135519 | 0.85 | EGLN3 (0.54) | EGLN3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3256798 | 0.81 | EGLN3 (0.77) | EGLN3TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2901279 | 0.81 | EGLN3 (0.52) | EGLN3ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL2901678 | 0.81 | EGLN3 (0.48) | EGLN3ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL13355930 | 0.80 | EGLN3 (0.58) | EGLN3ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL3252925 | 0.80 | EGLN3 (0.58) | EGLN3ALDH1A1KDM4EHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059549-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-05-27 | — | — | WO | disclosed |