Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 7/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 7/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 7/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 6/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 6/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3257323 | 0.91 | EGLN3 (0.54) | EGLN3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2901279 | 0.90 | EGLN3 (0.52) | EGLN3ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3132995 | 0.88 | EGLN3 (0.51) | EGLN3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3252291 | 0.86 | EGLN3 (0.50) | EGLN3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3138134 | 0.83 | EGLN3 (0.76) | EGLN3SMN1; SMN2TP53KMT2AMAPT | |
| SCHEMBL3135519 | 0.82 | EGLN3 (0.54) | EGLN3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3138099 | 0.81 | EGLN3 (0.64) | EGLN3ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL2903353 | 0.81 | ALDH1A1 (0.51) | EGLN3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3258148 | 0.80 | EGLN3 (0.50) | EGLN3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3256798 | 0.79 | EGLN3 (0.77) | EGLN3SMN1; SMN2TP53KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059549-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-05-27 | — | — | WO | disclosed |