Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL20954184 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL29150348 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL15310 | 1.00 | — | — | |
| Bicarbonate SCHEMBL47913 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL28734227 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL21612732 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL226943 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL28169410 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL7094615 | 0.96 | LMNA (0.47) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL5691551 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 800 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118336122-A | Electrolyte and sodium ion battery for stabilizing lamellar positive electrode by synergistic action of nitrile cosolvent and double salts | 河北工业大学 | 2024-07-12 | — | — | CN | claimed |
| EP-4398365-A1 | LITHIUM ION SECONDARY BATTERY AND NONAQUEOUS ELECTROLYTE SOLUTION | Kyocera Corporation (JP) | 2024-07-10 | — | — | EP | claimed |
| CN-117936751-A | Potassium-based layered oxide positive electrode material and preparation method and application thereof | 西安交通大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117720418-A | Continuous synthesis method of diethylene glycol bis (allyl carbonate) | 湖南化工研究院有限公司 | 2024-03-19 | — | — | CN | claimed |
| EP-3626721-B1 | SYNTHESIS OF ESTER AND AMIDE DERIVATIVES OF BETA-LACTAM NUCLEI | BONOMI PAOLO (FR) | 2023-09-06 | — | — | EP | claimed |
| CN-114456356-B | Polyperylene tetracarboxylic diimide, preparation method thereof and application thereof in lithium/sodium battery | 郑州大学 | 2023-06-20 | — | — | CN | claimed |
| CN-114479078-B | Naphthalimide polymer, preparation method thereof and application thereof in lithium/sodium battery | 郑州大学 | 2023-04-25 | — | — | CN | claimed |
| US-20220336863-A1 | RECHARGEABLE CALCIUM BATTERY | SYRACUSE UNIVERSITY (US) | 2022-10-20 | — | — | US | claimed |
| CN-113346131-B | Composite polymer gel solid electrolyte, preparation method thereof and application of lithium metal battery | 北京理工大学 | 2022-08-30 | — | — | CN | claimed |
| US-11355774-B2 | Thermally-drawn fiber including electrochemically active gels | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-06-07 | — | — | US | claimed |
| WO-2002004417-A1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF 4-AMINO-3-HYDROXYPYRROLE-2-CARBOXYLIC ACID | PHARMACIA CORPORAION (US) | 2002-01-17 | — | — | WO | claimed |
| EP-1137092-A1 | SECONDARY CELL | Sony Corporation (JP) | 2001-09-26 | — | — | EP | claimed |
| EP-0595924-B1 | PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 1999-04-14 | — | — | EP | claimed |
| US-5427710-A | Containing conjugated terpene, benzyl alcohol or derivative, organoclay rheological additive, optionally surfactant, additional terpene; biodegradable, nonflammable | STEVENS EDWIN (US) | 1995-06-27 | — | — | US | claimed |
| EP-0463969-B1 | New compounds of 4-aminobutyric acid, process for their preparation and pharmaceutical preparations containing them | ADIR (FR) | 1995-02-08 | — | — | EP | claimed |
| EP-0382641-B1 | Process for the preparation of ditertioalkyl dicarbonate | RHONE POULENC CHIMIE (FR) | 1994-07-06 | — | — | EP | claimed |
| EP-0372635-B1 | Method of preparing dialkyl and diallyl dicarbonates | AKZO NV (NL) | 1994-04-27 | — | — | EP | claimed |
| US-5243052-A | Mixed carbonate ester derivatives of quinophthalone dyes and their preparation | POLAROID CORPORATION (US) | 1993-09-07 | — | — | US | claimed |
| CN-1013422-B | NON-AQUEOUS SECONDARY CELL | SHOWA DENKO KK (JP) | 1991-07-31 | — | — | CN | claimed |
| CN-88101323-A | NON-AQUEOUS SECONDARY CELL | — | 1988-11-09 | — | — | CN | claimed |