Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL20954184 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL29150348 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL15310 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28734227 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL21612732 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL226943 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL325796 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL28169410 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL7094615 | 0.96 | LMNA (0.47) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL5691551 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4049841-B1 | HYBRID RESIN COMPOSITION | CUBICURE GMBH (AT) | 2026-03-18 | — | — | EP | claimed |
| US-12390987-B2 | Hybrid resin composition for the 3D-printing of objects | CUBICURE GMBH (AT) | 2025-08-19 | — | — | US | claimed |
| WO-2025071268-A1 | POLYESTER RESIN HAVING EXCELLENT MECHANICAL PROPERTIES AND BIODEGRADABILITY, AND PREPARATION METHOD THEREFOR | 주식회사 삼양사 | 2025-04-03 | — | — | WO | claimed |
| US-20240198582-A1 | HYBRID RESIN COMPOSITION FOR THE 3D-PRINTING OF OBJECTS | CUBICURE GMBH (AT) | 2024-06-20 | — | — | US | claimed |
| US-20240150390-A1 | NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-05-09 | — | — | US | claimed |
| WO-2024025084-A1 | PREPARATION METHOD FOR CARBON MATERIAL DISPERSION SOLUTION BY USING MULTI-FREQUENCY DISPERSION AND PREPARATION METHOD FOR POSITIVE ELECTRODE COMPRISING CARBON MATERIAL DISPERSION SOLUTION | 한국생산기술연구원 | 2024-02-01 | — | — | WO | claimed |
| EP-4286393-A1 | NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE | Daiichi Sankyo Company, Limited (JP) | 2023-12-06 | — | — | EP | claimed |
| CN-116867795-A | Novel method for producing antibody-immunostimulant conjugate | 第一三共株式会社 | 2023-10-10 | — | — | CN | claimed |
| CN-116410145-A | Preparation method of MRTX849 intermediate | 上海泓博智源医药股份有限公司 | 2023-07-11 | — | — | CN | claimed |
| US-20230155175-A1 | ELECTROLYTE FORMULATIONS FOR ELECTROCHEMICAL CELLS CONTAINING A SILICON ELECTRODE | HSBC VENTURES USA INC. | 2023-05-18 | — | — | US | claimed |
| EP-1244159-A1 | Electrochemical cell having an electrode with a dicarbonate additive in the electrode active mixture | WILSON GREATBATCH LTD. (US) | 2002-09-25 | — | — | EP | claimed |
| US-20020051911-A1 | Curable composition for polymer electrolyte | KANEKA CORPORATION (JP) | 2002-05-02 | — | — | US | claimed |
| US-20020042522-A1 | Process for the preparation of derivative of 4-amino-3-hydroxypyrrole-2-carboxylic acid | PHARMACIA CORPORATION | 2002-04-11 | — | — | US | claimed |
| US-6174629-B1 | ADDITION OF AT LEAST ONE DICARBONATE ADDITIVE TO AN ELECTROLYTE COMPRISING AN ALKALI METAL SALT DISSOLVED IN A SOLVENT MIXTURE THAT INCLUDES ETHYLENE CARBONATE, DIMETHYL CARBONATE, ETHYL METHYL CARBONATE AND DIETHYL CARBONATE | WILSON GREATBATCH LTD. | 2001-01-16 | — | — | US | claimed |
| EP-1005098-A2 | Alkali metal electrochemical cell having an improved cathode activated with a nonaqueous electrolyte having a passivation inhibitor additive | WILSON GREATBATCH LTD. (US) | 2000-05-31 | — | — | EP | claimed |
| US-6063526-A | AN ALKALI METAL, SOLID CATHODE, NONAQUEOUS ELECTROCHEMICAL CELL CAPABLE OF DELIVERING HIGH CURRENT PULSES, RAPIDLY RECOVERING ITS OPEN CIRCUIT VOLTAGE AND HAVING HIGH CURRENT CAPACITY; USE IN MEDICAL DEVICES SUCH AS DEFIBRILLATORS | WILSON GREATBATCH LTD. (US) | 2000-05-16 | — | — | US | claimed |
| EP-0951085-A1 | Dicarbonate additives for non-aqueous electrolyte in alkali metal electrochemical cells | WILSON GREATBATCH LTD. (US) | 1999-10-20 | — | — | EP | claimed |
| EP-0847098-A1 | A nonaqueous electrolyte secondary cell | DENSO CORPORATION (JP) | 1998-06-10 | — | — | EP | claimed |
| US-5750758-A | DEHYDRATION OF CARBONIC ACID | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-05-12 | — | — | US | claimed |
| US-4672129-A | Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1987-06-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150390-A1 | NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE | PAICS, COASY, CDS2 | LMNA 4487/4885ALDH1A1 4101/4885CA1 1496/4885 |
| US-20020042522-A1 | Process for the preparation of derivative of 4-amino-3-hydroxypyrrole-2-carboxylic acid | LIG4, POLL, HPD | LMNA 1469/4885ALDH1A1 3010/4885CA1 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.