Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL20954184 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL29150348 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL15310 | 1.00 | — | — | |
| Bicarbonate SCHEMBL47913 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL28734227 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL21612732 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL325796 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL28169410 | 1.00 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL7094615 | 0.96 | LMNA (0.47) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL5691551 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250107988-A1 | HAIR TREATMENT COMPOSITION AND METHODS FOR SMOOTHING HAIR | L'OREAL (FR) | 2025-04-03 | — | — | US | claimed |
| US-20250107981-A1 | METHODS FOR SMOOTHING HAIR | L'OREAL (FR) | 2025-04-03 | — | — | US | claimed |
| US-20250107989-A1 | HAIR TREATMENT COMPOSITIONS AND METHODS FOR SMOOTHING HAIR | L'OREAL (FR) | 2025-04-03 | — | — | US | claimed |
| WO-2025019731-A1 | HAIR TREATMENT COMPOSITIONS AND METHODS FOR SMOOTHING HAIR | L'OREAL (FR) | 2025-01-23 | — | — | WO | claimed |
| WO-2023035399-A1 | NONAQUEOUS ELECTROLYTE AND BATTERY | 宁波大学 | 2023-03-16 | — | — | WO | claimed |
| CN-110109311-B | All-solid-state electrochromic device and preparation method thereof | 东北大学秦皇岛分校 | 2022-02-01 | — | — | CN | claimed |
| CN-111393628-B | Application of organic metal complex and preparation method of polycarbonate prepolymer | 中国科学院过程工程研究所 | 2021-11-09 | — | — | CN | claimed |
| CN-112898461-A | Scratch-resistant lens and production process thereof | 严小红 | 2021-06-04 | — | — | CN | claimed |
| US-20200345606-A1 | COMPOSITIONS AND METHODS FOR REMOVING SEMI-PERMANENT HAIR DYES | L'OREAL (FR) | 2020-11-05 | — | — | US | claimed |
| WO-2020223168-A1 | COMPOSITIONS AND METHODS FOR REMOVING SEMI-PERMANENT HAIR DYES | L'OREAL (FR) | 2020-11-05 | — | — | WO | claimed |
| CN-107513018-B | Allyl diglycol carbonate and preparation method thereof | 山东清水化工有限公司 | 2020-09-29 | — | — | CN | claimed |
| CN-110813584-A | Environment-friendly high-rigidity pressing type sprayer and preparation method thereof | 浙江正庄实业有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110775430-A | Antibacterial anti-static double-layer emulsion bottle and preparation method thereof | 浙江正庄实业有限公司 | 2020-02-11 | — | — | CN | claimed |
| US-6106978-A | ENERGY DENSITY; DURABILITY | SONY CORPORATION (JP) | 2000-08-22 | — | — | US | claimed |
| US-5989744-A | Non-aqueous electrolyte secondary cell | SONY CORPORATION (JP) | 1999-11-23 | — | — | US | claimed |
| US-5814163-A | A MONOESTER, A METHYL ESTER, AN OLEFIN, AN ESTER ALCOHOL, PARTICULARLY TRIMETHYLPENTANEDIOL, MONO(2-METHYLPROPIONATE) | MACDERMID, INCORPORATED (US) | 1998-09-29 | — | — | US | claimed |
| CN-1175098-A | Accumulator with no water electrolytic solution | SONY CORP (JP) | 1998-03-04 | — | — | CN | claimed |
| US-20260092137-A1 | URETHANE RESIN COMPOSITION AND BUILDING INSULATION METHOD | NIPPON AQUA CO LTD (JP) | 2026-04-02 | — | — | US | disclosed |
| US-5292601-A | Nonaqueous electrolyte secondary battery | SONY CORPORATION (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0486950-A1 | Nonaqueous electrolyte secondary battery | SONY CORPORATION (JP) | 1992-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250107989-A1 | HAIR TREATMENT COMPOSITIONS AND METHODS FOR SMOOTHING HAIR | SHH, CD44, DSC1 | LMNA 3086/4885ALDH1A1 4019/4885CA1 75/4885 |
| US-20200345606-A1 | COMPOSITIONS AND METHODS FOR REMOVING SEMI-PERMANENT HAIR DYES | CYCS, TYR, DNMT1 | LMNA 1125/4885ALDH1A1 1605/4885CA1 876/4885 |
| US-20260092137-A1 | URETHANE RESIN COMPOSITION AND BUILDING INSULATION METHOD | PUF60, PFAS, ITPA | LMNA 3409/4885ALDH1A1 2776/4885CA1 996/4885 |
| US-20250107988-A1 | HAIR TREATMENT COMPOSITION AND METHODS FOR SMOOTHING HAIR | FZD7, DSC1, COL14A1 | LMNA 1197/4885ALDH1A1 4395/4885CA1 708/4885 |
| US-20250107981-A1 | METHODS FOR SMOOTHING HAIR | FZD7, CROCC, DSC1 | LMNA 1827/4885ALDH1A1 3511/4885CA1 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.