Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 15/20 | 0.51 |
| ▸ | TRPM4 | Q8TD43 | 8/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6194447 | 0.83 | TRPM5 (0.43) | TRPM5TRPM4 | |
| SCHEMBL19098966 | 0.81 | PNMT (0.61) | CREBBPPNMT | |
| SCHEMBL471068 | 0.79 | TRPM5 (0.51) | TRPM5TRPM4 | |
| SCHEMBL7297572 | 0.76 | PDE3B (0.41) | CREBBPPNMT | |
| SCHEMBL7297564 | 0.76 | PDE3B (0.41) | CREBBPPNMT | |
| SCHEMBL2450511 | 0.74 | CREBBP (0.59) | TRPM5CREBBPPNMT | |
| SCHEMBL1193549 | 0.74 | CREBBP (0.59) | TRPM5CREBBPPNMT | |
| SCHEMBL30681442 | 0.74 | CREBBP (0.59) | TRPM5CREBBPPNMT | |
| SCHEMBL550431 | 0.74 | CREBBP (0.59) | TRPM5CREBBPPNMT | |
| SCHEMBL30288510 | 0.74 | CREBBP (0.59) | TRPM5CREBBPPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330454-B1 | BENZOPYRANYL HETEROCYCLE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HITEK CO LTD (KR) | 2010-05-19 | — | — | EP | disclosed |
| EP-1330454-A4 | BENZOPYRANYL HETEROCYCLE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2008-03-19 | — | — | EP | disclosed |
| EP-1330454-A1 | BENZOPYRANYL HETEROCYCLE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dongbu Hannong Chemical Co., Ltd. (KR) | 2003-07-30 | — | — | EP | disclosed |
| US-6413983-B1 | COUPLING EPOXIDE WITH INDOLE OR QUINOLINE COMPOUND; PROTECT-ING HEART, BRAIN, RETINA AND NEURONAL CELL FROM ?ISCHEMIA-REPERFUSION? INJURY; SUPPRESSING LIPID PEROXIDATION | DONGBU HANNONG CHEMICAL CO. LTD. (KR) | 2002-07-02 | — | — | US | disclosed |
| WO-2002030925-A1 | BENZOPYRANYL HETEROCYCLE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO., LTD (KR) | 2002-04-18 | — | — | WO | disclosed |