Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3256210 | 0.87 | SCN1A (0.38) | SLC22A12CYP2C9SLC22A6SLC22A8SLC22A11 | |
| SCHEMBL3259074 | 0.84 | HTT (0.49) | ALDH1A1AKT1KDM1ASCN1ASCN5A | |
| SCHEMBL3255395 | 0.82 | KCNA5 (0.46) | ALDH1A1 | |
| SCHEMBL3256778 | 0.81 | P2RY1 (0.49) | AKT1KDM1AMMP7 | |
| SCHEMBL3257453 | 0.79 | SCN8A (0.40) | MEN1ALDH1A1KMT2ACYP2C9SCN1A | |
| SCHEMBL3256970 | 0.79 | ALOX12 (0.46) | MEN1KMT2ASCN1ASCN5ASCN8A | |
| SCHEMBL3253281 | 0.78 | SCN1A (0.44) | SCN1ASCN5ASCN8A | |
| SCHEMBL3256058 | 0.78 | MEP1B (0.42) | ALDH1A1SCN1ASCN5ASCN8A | |
| SCHEMBL3253802 | 0.78 | SCD (0.52) | SLC22A12MEN1ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL3256119 | 0.77 | SCN8A (0.40) | MEN1ALDH1A1KMT2ACYP2C9SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461325-B1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2010-05-26 | — | — | EP | claimed |