Ethylene Glycol

Ethylene Glycol

SCHEMBL3259443

O=C(O)CC(C(=O)O)N1C(=O)CCC1=O.OCCO

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
PKM P14618 1/20 0.51
KMT2A Q03164 2/20 0.41
ATM Q13315 1/20 0.41
MME P08473 1/20 0.36
TP53 P04637 2/20 0.36
POLB P06746 3/20 0.33
MAPT P10636 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 2/20 0.33
SLC1A2 P43004 1/20 0.33
PPM1B O75688 1/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
NFKB1 P19838 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL4564907 1.00 ALDH1A1 (0.51) ALDH1A1PKMKMT2AATMMME
Ethylene Glycol SCHEMBL43938 1.00 ALDH1A1 (0.51) ALDH1A1PKMKMT2AATMMME
SCHEMBL30302184 0.94 ALDH1A1 (0.53) ALDH1A1PKMKMT2AATMMME
SCHEMBL604671 0.94 ALDH1A1 (0.56) ALDH1A1PKMKMT2AATMMME
SCHEMBL2332165 0.94 ALDH1A1 (0.56) ALDH1A1PKMKMT2AATMMME
Thioglycolic Acid SCHEMBL27759668 0.93 ALDH1A1 (0.46) ALDH1A1PKMKMT2AATMMME
Ethylene SCHEMBL8387032 0.91 ALDH1A1 (0.53) ALDH1A1PKMKMT2AATMMME
Ethylene SCHEMBL29141463 0.91 ALDH1A1 (0.53) ALDH1A1PKMKMT2AATMMME
Ethylene Glycol SCHEMBL9329904 0.91 ALDH1A1 (0.44) ALDH1A1PKMKMT2AATMMME
Propionic Acid SCHEMBL7866660 0.87 ALDH1A1 (0.50) ALDH1A1PKMKMT2AATMMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115177741-A Metal-organic composite nano-drug and preparation method and application thereof 北京科技大学 2022-10-14 CN claimed
CN-111587124-B ROR1 antibody immunoconjugates 维洛斯生物股份有限公司 2024-01-12 CN disclosed
WO-2022217733-A1 MEDICAL HYDROGEL AND PREPARATION METHOD THEREFOR AND USE THEREOF 北京博辉瑞进生物科技有限公司 2022-10-20 WO disclosed
CN-101939025-B Therapeutic agent for pruritus CHUGAI PHARMACEUTICAL CO LTD 2015-03-25 CN disclosed
CN-104162155-A Therapeutic agent for pruritus CHUGAI PHARMACEUTICAL CO LTD 2014-11-26 CN disclosed
US-20130048077-A1 GEL ELECTROLYTE AND DYE-SENSITIZED SOLAR CELL USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2013-02-28 US disclosed
US-8314194-B2 Gel electrolyte and dye-sensitized solar cell using the same SAMSUNG SDI CO., LTD. (KR) 2012-11-20 US disclosed
CN-101516388-B Glycosylation of peptides by O-linked glycosylation sequences NOVO NORDISK AS 2012-10-31 CN disclosed
CN-101939025-A Therapeutic agent for pruritus CHUGAI PHARMACEUTICAL CO LTD 2011-01-05 CN disclosed
US-20100051097-A1 GEL ELECTROLYTE AND DYE-SENSITIZED SOLAR CELL USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-03-04 US disclosed
CN-101594883-A Diagnosis and treatment of cancer using anti-EREG antibodies FORERUNNER PHARMA RES CO LTD U (JP) 2009-12-02 CN disclosed
CN-101516388-A Glycosylation of peptides by O-linked glycosylation sequences NEOSE TECHNOLOGIES INC (DK) 2009-08-26 CN disclosed
CN-101505791-A Diagnosis and treatment of cancer using anti-desmoglein-3 antibody FORERUNNER PHARMA RES CO LTD (JP) 2009-08-12 CN disclosed
CN-1638809-A Coupling low-molecular substances to a modified polysaccharide FRESENIUS CABI GMBH (DE) 2005-07-13 CN disclosed
CN-1638808-A Coupling proteins to a modified polysaccharide FRESENIUS CABI GMBH (DE) 2005-07-13 CN disclosed
EP-0067029-B1 OXYGEN CARRIER AJINOMOTO CO., INC. (JP) 1986-04-30 EP disclosed
US-4412989-A POLYOXYALKYLENE GLYCOL COUPLED TO A HEMOGLOBIN OR HEMOGLOBIN DERIVATIVE AJINOMOTO COMPANY INCORPORATED (JP) 1983-11-01 US disclosed
EP-0067029-A2 Oxygen carrier AJINOMOTO CO., INC. (JP) 1982-12-15 EP disclosed