Ethylene Glycol

Ethylene Glycol

SCHEMBL4564907

O=C(O)C[C@@H](C(=O)O)N1C(=O)CCC1=O.OCCO

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
PKM P14618 1/20 0.51
KMT2A Q03164 2/20 0.41
ATM Q13315 1/20 0.41
MME P08473 1/20 0.36
TP53 P04637 2/20 0.36
POLB P06746 3/20 0.33
MAPT P10636 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 2/20 0.33
SLC1A2 P43004 1/20 0.33
PPM1B O75688 1/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
NFKB1 P19838 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL43938 1.00 ALDH1A1 (0.51) ALDH1A1PKMKMT2AATMMME
Ethylene Glycol SCHEMBL3259443 1.00 ALDH1A1 (0.51) ALDH1A1PKMKMT2AATMMME
SCHEMBL30302184 0.94 ALDH1A1 (0.53) ALDH1A1PKMKMT2AATMMME
SCHEMBL604671 0.94 ALDH1A1 (0.56) ALDH1A1PKMKMT2AATMMME
SCHEMBL2332165 0.94 ALDH1A1 (0.56) ALDH1A1PKMKMT2AATMMME
Thioglycolic Acid SCHEMBL27759668 0.93 ALDH1A1 (0.46) ALDH1A1PKMKMT2AATMMME
Ethylene SCHEMBL8387032 0.91 ALDH1A1 (0.53) ALDH1A1PKMKMT2AATMMME
Ethylene SCHEMBL29141463 0.91 ALDH1A1 (0.53) ALDH1A1PKMKMT2AATMMME
Ethylene Glycol SCHEMBL9329904 0.91 ALDH1A1 (0.44) ALDH1A1PKMKMT2AATMMME
Propionic Acid SCHEMBL7866660 0.87 ALDH1A1 (0.50) ALDH1A1PKMKMT2AATMMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1578450-A4 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING ACCESS PHARMACEUTICALS AUSTRAL (AU) 2009-06-17 EP claimed
EP-1578450-A1 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING Access Pharmaceuticals Australia Pty Ltd (AU) 2005-09-28 EP claimed
WO-2004045647-A1 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING ACCESS PHARMACEUTICALS AUSTRALIA PTY LTD (AU) 2004-06-03 WO claimed