Ethylene Glycol

Ethylene Glycol

SCHEMBL9329904

CC(C(=O)O)N1C(=O)CCC1=O.O=C(O)CC(C(=O)O)N1C(=O)CCC1=O.O=C(O)CC(C(=O)O)N1C(=O)CCC1=O.OCCO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
PKM P14618 1/20 0.44
SLC1A2 P43004 2/20 0.40
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
MEN1 O00255 1/20 0.39
MME P08473 1/20 0.38
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
CSNK2A1 P68400 1/20 0.35
TP53 P04637 1/20 0.34
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL3259443 0.91 ALDH1A1 (0.51) ALDH1A1PKMSLC1A2KMT2AATM
Ethylene Glycol SCHEMBL43938 0.91 ALDH1A1 (0.51) ALDH1A1PKMSLC1A2KMT2AATM
Ethylene Glycol SCHEMBL4564907 0.91 ALDH1A1 (0.51) ALDH1A1PKMSLC1A2KMT2AATM
Ethylene Glycol SCHEMBL3521351 0.87 SLC1A2 (0.47) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL30302184 0.85 ALDH1A1 (0.53) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL2332165 0.85 ALDH1A1 (0.56) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL604671 0.85 ALDH1A1 (0.56) ALDH1A1PKMSLC1A2KMT2AATM
Thioglycolic Acid SCHEMBL27759668 0.84 ALDH1A1 (0.46) ALDH1A1PKMSLC1A2KMT2AATM
Propionic Acid SCHEMBL7866660 0.82 ALDH1A1 (0.50) ALDH1A1PKMSLC1A2KMT2AATM
Ethylene SCHEMBL29141463 0.82 ALDH1A1 (0.53) ALDH1A1PKMSLC1A2KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0359996-B1 Synthetic amino acid-and/or peptide-containing graft copolymers AL MARZOOK UNITED COMMERCIAL C (KW) 1994-04-13 EP disclosed
EP-0359996-A2 Synthetic amino acid-and/or peptide-containing graft copolymers Al Marzook United Commercial Co. (KW) 1990-03-28 EP disclosed
US-4908404-A Water soluble high molecular weight cationic graft polymer BIOPOLYMERS, INC. (US) 1990-03-13 US disclosed