SCHEMBL3259552

SCHEMBL3259552

C=CC(OC(C)=O)c1cccc2ccoc12

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11781019 0.74 KDM4E (0.38) KDM4EPOLBMAPTHSD17B10
SCHEMBL5836381 0.72 KMT2A (0.46) KDM4EPOLBMAPTHSD17B10
SCHEMBL9241746 0.71 BACE1 (0.39)
SCHEMBL16844552 0.68 CYP1A2 (0.36) MAPT
SCHEMBL16855175 0.68 CYP1A2 (0.36) MAPT
SCHEMBL30701213 0.68 CYP1A2 (0.36) MAPT
SCHEMBL15495778 0.67 ADORA2A (0.54) KDM4EPOLBMAPTHSD17B10
SCHEMBL3795346 0.67 GABRA1 (0.41) MAPT
SCHEMBL61038 0.66 CYP3A4 (0.50) KDM4EMAPTHSD17B10
SCHEMBL7649073 0.66 UGT2B7 (0.45) KDM4EMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671055-B2 surprisingly active in the control of insects and acarids; admixture with pesticides, plant growth regulators, fertilizers and soil conditioners FMC CORPORATION (US) 2010-03-02 US disclosed
US-20080261993-A1 Insecticidal 3-(Dihaloalkenyl) Phenyl Derivatives BAYER CROPSCIENCE AG (DE) 2008-10-23 US disclosed
EP-1805152-A2 INSECTICIDAL 3-(DIHALOALKENYL) PHENYL DERIVATIVES Bayer CropScience AG (DE) 2007-07-11 EP disclosed
WO-2006047438-A2 INSECTICIDAL 3-(DIHALOALKENYL) PHENYL DERIVATIVES BAYER CROPSCIENCE AG (DE) 2006-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261993-A1 Insecticidal 3-(Dihaloalkenyl) Phenyl Derivatives DDT, L3MBTL4, L3MBTL3 KDM4E 1490/4885POLB 3573/4885MAPT 4448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.