Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.69 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | F10 | P00742 | 2/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425465 | 0.88 | MEN1 (0.79) | KMT2AMEN1NOD2NOD1KDM4E | |
| SCHEMBL18202169 | 0.88 | MEN1 (0.74) | KMT2AMEN1NOD2NOD1KDM4E | |
| SCHEMBL16201674 | 0.88 | MEN1 (0.74) | KMT2AMEN1NOD2NOD1KDM4E | |
| SCHEMBL3259707 | 0.86 | NOD2 (0.71) | KMT2AMEN1NOD2NOD1KDM4E | |
| SCHEMBL10629278 | 0.85 | KMT2A (0.71) | KMT2AMEN1NOD2NOD1KDM4E | |
| SCHEMBL28669136 | 0.85 | NOD2 (0.70) | KMT2AMEN1NOD2NOD1KDM4E | |
| SCHEMBL14994342 | 0.84 | MEN1 (0.70) | KMT2AMEN1NOD2NOD1KDM4E | |
| SCHEMBL4798323 | 0.84 | NOD2 (0.85) | KMT2AMEN1NOD2NOD1KDM4E | |
| SCHEMBL23052993 | 0.83 | NOD2 (0.64) | KMT2AMEN1NOD2NOD1KDM4E | |
| SCHEMBL6752352 | 0.82 | KDM4E (0.71) | KMT2AMEN1NOD2NOD1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |