SCHEMBL3259795

SCHEMBL3259795

C=CC(N)c1cccc2c1C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.53
MAPT P10636 4/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
HPGD P15428 2/20 0.53
HTT P42858 2/20 0.53
SMAD3 P84022 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
CYP2C19 P33261 1/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53
PRMT1 Q99873 1/20 0.53
ACE2 Q9BYF1 1/20 0.53
ALDH1A1 P00352 3/20 0.51
ALOX12 P18054 2/20 0.51
ALOX15 P16050 2/20 0.51
HSD17B10 Q99714 2/20 0.51
CYP2C9 P11712 1/20 0.51
BRCA1 P38398 1/20 0.51
LMNA P02545 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5766096 0.87 FTO (0.59) FTOMAPTMEN1KMT2AHPGD
SCHEMBL6547973 0.83 FTO (0.54) FTOMAPTMEN1KMT2AHPGD
SCHEMBL24943859 0.82 FTO (0.59) FTOMAPTMEN1KMT2AHPGD
SCHEMBL7526450 0.82 ALDH1A1 (0.59) FTOMAPTMEN1KMT2AHPGD
SCHEMBL7524436 0.81 FTO (0.56) FTOMAPTMEN1KMT2AHPGD
SCHEMBL18641320 0.80 FTO (0.59) FTOMAPTMEN1KMT2AHPGD
SCHEMBL7030299 0.80 FTO (0.53) FTOMAPTMEN1KMT2AHPGD
SCHEMBL4519856 0.78 FTO (0.63) FTOMAPTMEN1KMT2AHPGD
SCHEMBL82165 0.78 FTO (0.63) FTOMAPTMEN1KMT2AHPGD
SCHEMBL6247181 0.78 FTO (0.63) FTOMAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140186831-A1 Solid Phases Optimized for Chemiluminescent Detection Life Technologies Corporation (US) 2014-07-03 US disclosed
EP-2163897-A1 Solid phases optimized for chemiluminescent detection Applied Biosystems, LLC (US) 2010-03-17 EP disclosed
EP-1470422-B8 SOLID PHASES OPTIMIZED FOR CHEMILUMINESCENT DETECTION APPLIED BIOSYSTEMS LLC (US) 2009-10-07 EP disclosed
EP-2101174-A1 Solid phases optimized for chemiluminescent detection Applied Biosystems, LLC (US) 2009-09-16 EP disclosed
EP-1470422-B1 SOLID PHASES OPTIMIZED FOR CHEMILUMINESCENT DETECTION APPLERA CORP (US) 2009-07-15 EP disclosed
US-20080227124-A1 Multilayer support of polylactone or polyamide and cationic polymer; bioassay; kits APPLIED BIOSYSTEMS, INC. 2008-09-18 US disclosed
US-7368296-B2 Multilayer support of polylactone or polyamide and cationic polymer APPLIED BIOSYSTEMS (US) 2008-05-06 US disclosed
EP-1470422-A4 SOLID PHASES OPTIMIZED FOR CHEMILUMINESCENT DETECTION APPLERA CORP (US) 2006-06-07 EP disclosed
EP-1470422-A2 SOLID PHASES OPTIMIZED FOR CHEMILUMINESCENT DETECTION Applera Corporation (US) 2004-10-27 EP disclosed
WO-2003062790-A2 SOLID PHASES OPTIMIZED FOR CHEMILUMINESCENT DETECTION APPLERA CORPORATION (US) 2003-07-31 WO disclosed
US-20030134286-A1 Multilayer support of polylactone or polyamide and cationic polymer APPLIED BIOSYSTEMS, INC. 2003-07-17 US disclosed