Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5766096 | 0.85 | FTO (0.59) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL7526450 | 0.82 | ALDH1A1 (0.59) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL24943859 | 0.82 | FTO (0.59) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL6547973 | 0.81 | FTO (0.54) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL7524436 | 0.81 | FTO (0.56) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL3730178 | 0.80 | FTO (0.59) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL3259795 | 0.80 | FTO (0.53) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL2019142 | 0.79 | FTO (0.63) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL4519856 | 0.78 | FTO (0.63) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL2360878 | 0.78 | FTO (0.63) | FTOMAPTHPGDMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230115088-A1 | 3-Methylideneoxan-4-One Compounds and Substituted Derivates Thereof as Inhibitors of Telomerase | NORTHWESTERN UNIVERSITY | 2023-04-13 | — | — | US | disclosed |
| US-11518750-B2 | 3-methylideneoxan-4-one compounds and substituted derivatives thereof as inhibitors of telomerase | NORTHWESTERN UNIVERSITY (US) | 2022-12-06 | — | — | US | disclosed |
| US-20210070725-A1 | 3-METHYLIDENEOXAN-4-ONE COMPOUNDS AND SUBSTITUTED DERIVATIVES THEREOF AS INHIBITORS OF TELOMERASE | NORTHWESTERN UNIVERSITY (US) | 2021-03-11 | — | — | US | disclosed |
| US-6589744-B2 | Fluorescence polarization to detect the change in mass of a fluorescently labeled oligo to determine presence | SYNGENTA PARTICIPATIONS AG (CH) | 2003-07-08 | — | — | US | disclosed |
| US-20030099953-A1 | Method and kit for identification for nucleic acid modification enzymes and inhibitors thereof | DUTCHER ROBERT CALVIN | 2003-05-29 | — | — | US | disclosed |
| US-5786139-A | MEASURING FLUORESCENCE POLARIZATION | PANVERA CORPORATION (US) | 1998-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070725-A1 | 3-METHYLIDENEOXAN-4-ONE COMPOUNDS AND SUBSTITUTED DERIVATIVES THEREOF AS INHIBITORS OF TELOMERASE | TERT, POT1, TERF2 | FTO 2371/4885MAPT 2269/4885HPGD 477/4885 |
| US-20230115088-A1 | 3-Methylideneoxan-4-One Compounds and Substituted Derivates Thereof as Inhibitors of Telomerase | TERT, POT1, TERF2 | FTO 2262/4885MAPT 2527/4885HPGD 331/4885 |
| US-11518750-B2 | 3-methylideneoxan-4-one compounds and substituted derivatives thereof as inhibitors of telomerase | TERT, POT1, TERF2 | FTO 2371/4885MAPT 2269/4885HPGD 477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.