Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 8/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.47 |
| ▸ | F11 | P03951 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899959 | 0.85 | FFAR1 (0.48) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL15168853 | 0.84 | LPL (0.41) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL5254853 | 0.83 | LPL (0.55) | LPLLIPGF11ESR2ALDH1A1 | |
| SCHEMBL429722 | 0.83 | LMNA (0.53) | LPLLIPGF11ESR2ALDH1A1 | |
| SCHEMBL1354581 | 0.83 | LPL (0.54) | LPLLIPGF11ALDH1A1KDM4E | |
| SCHEMBL3319981 | 0.83 | LPL (0.54) | LPLLIPGF11ESR2ALDH1A1 | |
| SCHEMBL19211668 | 0.82 | LPL (0.48) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL1428042 | 0.82 | LPL (0.44) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL427977 | 0.81 | HRH3 (0.56) | LPLLIPGF11ALDH1A1KDM4E | |
| SCHEMBL25275022 | 0.81 | LIPG (0.40) | LPLLIPGF11F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010184-A1 | [1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |