Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.52 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 5/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299906 | 0.81 | ALDH1A1 (0.70) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL28265821 | 0.80 | ESR1 (0.57) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL902308 | 0.80 | ALDH1A1 (0.60) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL8003446 | 0.78 | KDM1A (0.45) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL30857473 | 0.77 | ALDH1A1 (0.64) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL11905392 | 0.77 | ALDH1A1 (0.64) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL28265823 | 0.74 | ALDH1A1 (0.53) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL30853545 | 0.74 | ALDH1A1 (0.58) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL29712310 | 0.74 | ALDH1A1 (0.58) | ALDH1A1GLAHPGDMAPTACHE | |
| SCHEMBL11690096 | 0.74 | ALDH1A1 (0.58) | ALDH1A1GLAHPGDMAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747701-B1 | Micelle protection assay | GEN PROBE INC (US) | 2001-12-05 | — | — | EP | claimed |
| CN-107311925-A | One kind contains acridine compounds and its organic luminescent device | 长春海谱润斯科技有限公司 | 2017-11-03 | — | — | CN | disclosed |
| US-7651746-B2 | Halogenated bisdiarylaminopolycyclic aromatic compounds and polymers thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20070126345-A1 | Halogenated bisdiarylaminopolycylic aromatic compounds and polymers thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | US | disclosed |
| WO-2005049546-A1 | HALOGENATED BISDIARYLAMINOPOLYCYLIC AROMATIC COMPOUNDS AND POLYMERS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070126345-A1 | Halogenated bisdiarylaminopolycylic aromatic compounds and polymers thereof | AHR, AADAC, ARNT | ALDH1A1 667/4885GLA 2598/4885HPGD 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.