SCHEMBL902308

SCHEMBL902308

Brc1cccc2nc3ccccc3cc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
GLA P06280 3/20 0.60
HPGD P15428 3/20 0.60
KMT2A Q03164 3/20 0.60
RAB9A P51151 3/20 0.60
GAA P10253 2/20 0.60
KDM4E B2RXH2 2/20 0.60
NPC1 O15118 1/20 0.60
LMNA P02545 1/20 0.60
POLB P06746 1/20 0.60
PTBP1 P26599 1/20 0.60
RCE1 Q9Y256 1/20 0.60
MAPT P10636 3/20 0.56
ACHE P22303 2/20 0.56
BACE1 P56817 1/20 0.50
TDP1 Q9NUW8 2/20 0.47
NQO2 P16083 3/20 0.43
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
KCNH2 Q12809 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28265823 0.85 ALDH1A1 (0.53) ALDH1A1GLAHPGDKMT2ARAB9A
SCHEMBL3260285 0.80 ALDH1A1 (0.52) ALDH1A1GLAHPGDKMT2ARAB9A
SCHEMBL4299906 0.80 ALDH1A1 (0.70) ALDH1A1GLAHPGDKMT2ARAB9A
SCHEMBL4014126 0.78 KMT2A (0.64) ALDH1A1GLAHPGDKMT2ARAB9A
Acridine SCHEMBL27603600 0.77 ALDH1A1 (0.94) ALDH1A1GLAHPGDKMT2ARAB9A
SCHEMBL28998065 0.76 ALDH1A1 (0.61) ALDH1A1GLAHPGDKMT2ARAB9A
SCHEMBL11905392 0.76 ALDH1A1 (0.64) ALDH1A1GLAHPGDKMT2ARAB9A
SCHEMBL30857473 0.76 ALDH1A1 (0.64) ALDH1A1GLAHPGDKMT2ARAB9A
SCHEMBL28573272 0.75 ALDH1A1 (0.56) ALDH1A1GLAHPGDKMT2ARAB9A
SCHEMBL291182 0.75 ALDH1A1 (0.60) ALDH1A1GLAHPGDKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213325-A Preparation method and application of 10-methyl-9, 10-acridan-9-thiocarboxylic acid-4-chlorophenyl ester 北京富盛嘉华医药科技有限公司 2022-03-22 CN claimed
US-20250255778-A1 SCAFFOLDS FOR SELECTIVE SCAVENGING OF STORAGE LESION FROM BIOLOGICAL MATERIAL AND METHODS THEREOF INSTITUTE FOR STEM CELL SCIENCE AND REGENERATIVE MEDICINE (IN) 2025-08-14 US disclosed
EP-4493140-A1 SCAFFOLDS FOR SELECTIVE SCAVENGING OF STORAGE LESION FROM BIOLOGICAL MATERIAL AND METHODS THEREOF Institute for Stem Cell Science and Regenerative Medicine (Instem) (IN) 2025-01-22 EP disclosed
WO-2023175576-A9 SCAFFOLDS FOR SELECTIVE SCAVENGING OF STORAGE LESION FROM BIOLOGICAL MATERIAL AND METHODS THEREOF INSTITUTE FOR STEM CELL SCIENCE AND REGENERATIVE MEDICINE (IN) 2023-11-16 WO disclosed
WO-2023175576-A1 SCAFFOLDS FOR SELECTIVE SCAVENGING OF STORAGE LESION FROM BIOLOGICAL MATERIAL AND METHODS THEREOF INSTITUTE FOR STEM CELL SCIENCE AND REGENERATIVE MEDICINE (IN) 2023-09-21 WO disclosed
CN-114213325-B Preparation method and application of 10-methyl-9, 10-acridine dihydride-9-thiocarboxylic acid-4-chlorophenyl ester 北京富盛嘉华医药科技有限公司 2023-06-23 CN disclosed
CN-114213325-A Preparation method and application of 10-methyl-9, 10-acridan-9-thiocarboxylic acid-4-chlorophenyl ester 北京富盛嘉华医药科技有限公司 2022-03-22 CN disclosed
CN-114149368-A Organic room temperature electrophosphorescent material, preparation method and organic electroluminescent diode thereof 云南大学 2022-03-08 CN disclosed
CN-111253393-B Long-life triplet exciton confinement material and application thereof in OLED (organic light emitting diode) device 北京大学 2022-01-25 CN disclosed
CN-111253393-A Long-life triplet exciton confinement material and application thereof in OLED (organic light emitting diode) device 北京大学 2020-06-09 CN disclosed
CN-109336940-A Acridone derivatives and its preparation method and application of the one kind containing galactolipin 河南师范大学 2019-02-15 CN disclosed
US-20130310411-A1 NOVEL ACRIDINE DERIVATIVES PHARMINOX LIMITED (GB) 2013-11-21 US disclosed
EP-2621929-A1 NOVEL ACRIDINE DERIVATIVES Pharminox Limited (GB) 2013-08-07 EP disclosed
WO-2012042265-A1 NOVEL ACRIDINE DERIVATIVES PHARMINOX LIMITED (GB) 2012-04-05 WO disclosed
CN-100513405-C Chiral ionic compound containing pyrrolidinyl radical and its preparation and application UNIV ZHEJIANG TECHNOLOGY (CN) 2009-07-15 CN disclosed
CN-101423757-A High performance electroluminescent organic material and application thereof in organic EL device UNIV JILIN (CN) 2009-05-06 CN disclosed
CN-1974566-A Chiral ionic compound containing pyrrolidinyl radical and its prepn and application UNIV ZHEJIANG POLYTECHNIC (CN) 2007-06-06 CN disclosed
US-5151518-A N-arylation of isatins ABBOTT LABORATORIES (US) 1992-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130310411-A1 NOVEL ACRIDINE DERIVATIVES TERT, NAT10, POT1 ALDH1A1 41/4885GLA 701/4885HPGD 1861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.