SCHEMBL3260428

SCHEMBL3260428

C=Cc1ccc2c(ccc3ccccc32)c1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.45
HSD17B10 Q99714 4/20 0.44
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.44
HPGD P15428 3/20 0.44
GLA P06280 2/20 0.44
MEN1 O00255 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.44
WDR5 P61964 1/20 0.42
LDHA P00338 1/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
CDC25B P30305 1/20 0.40
MAPT P10636 2/20 0.40
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL374659 0.92 HSD17B10 (0.53) HSD17B10ALDH1A1KDM4EHPGDGLA
SCHEMBL3261516 0.81 MEN1 (0.53) HSD17B10ALDH1A1KDM4EHPGDGLA
SCHEMBL11865600 0.80 ALDH1A1 (0.41) HPRT1HSD17B10ALDH1A1KDM4EHPGD
SCHEMBL26200101 0.78 ALDH1A1 (0.41) HPRT1HSD17B10ALDH1A1KDM4EHPGD
SCHEMBL505905 0.77 KDM4E (0.41) HSD17B10ALDH1A1KDM4EHPGDGLA
SCHEMBL28592109 0.77 NCEH1 (0.48) HSD17B10ALDH1A1KDM4EHPGDGLA
SCHEMBL929073 0.76 HPRT1 (0.52) HPRT1HSD17B10ALDH1A1KDM4EHPGD
SCHEMBL183135 0.76 WDR5 (0.61) HPRT1HSD17B10ALDH1A1KDM4EHPGD
SCHEMBL31613859 0.76 WDR5 (0.61) HPRT1HSD17B10ALDH1A1KDM4EHPGD
SCHEMBL11928243 0.76 WDR5 (0.61) HPRT1HSD17B10ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100036188-A1 MOLECULARLY IMPRINTED POLYMER, PROCESS FOR PRODUCTION THEREOF AND PROCESS FOR THE SELECTIVE TREATMENT OF POORLY DEGRADABLE AND/OR TOXIC COMPOUNDS IN LIQUIDS KIST-EUROPE FORSCHUNGSGESELLSCHAFT MBH (DE) 2010-02-11 US disclosed