SCHEMBL505905

SCHEMBL505905

C=Cc1ccc2ccccc2c1C(=C)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.41
ALDH1A1 P00352 6/20 0.41
HPGD P15428 6/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
HSD17B10 Q99714 3/20 0.41
GLA P06280 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
ABCG2 Q9UNQ0 2/20 0.40
WDR5 P61964 1/20 0.39
MAPT P10636 2/20 0.38
GAA P10253 2/20 0.38
CRHBP P24387 1/20 0.38
HTT P42858 1/20 0.38
CRHR2 Q13324 1/20 0.38
LDHA P00338 1/20 0.38
ATM Q13315 1/20 0.37
NR4A1 P22736 1/20 0.37
NR4A2 P43354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28836322 0.86 KDM4E (0.37) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL374659 0.85 HSD17B10 (0.53) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL26200101 0.84 ALDH1A1 (0.41) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL11865600 0.83 ALDH1A1 (0.41) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL78738 0.81 KDM4E (0.43) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL27600777 0.81 KDM4E (0.43) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL28592109 0.80 NCEH1 (0.48) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL9572195 0.78 ALDH1A1 (0.38) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL3260428 0.77 HPRT1 (0.45) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL13871446 0.76 ABCC9 (0.38) KDM4EALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9233846-B2 Formation and encapsulation of molecular bilayer and monolayer membranes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-01-12 US disclosed
US-8821702-B2 Devices and methods for electroosmotic transport of non-polar solvents EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-09-02 US disclosed
US-20120186977-A1 DEVICES AND METHODS FOR ELECTROOSMOTIC TRANSPORT OF NON-POLAR SOLVENTS CRESTLINE DIRECT FINANCE, L.P. 2012-07-26 US disclosed
WO-2012026942-A1 DEVICES AND METHODS FOR ELECTROOSMOTIC TRANSPORT OF NON-POLAR SOLVENTS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2012-03-01 WO disclosed
US-20120025414-A1 FORMATION AND ENCAPSULATION OF MOLECULAR BILAYER AND MONOLAYER MEMBRANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-02-02 US disclosed
US-8038885-B2 Formation and encapsulation of molecular bilayer and monolayer membranes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-10-18 US disclosed
US-20090170118-A1 Formation and Encapsulation of Molecular Bilayer and Monolayer Membranes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2009-07-02 US disclosed
WO-2007047498-A2 FORMATION AND ENCAPSULATION OF MOLECULAR BILAYER AND MONOLAYER MEMBRANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-04-26 WO disclosed