Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19119222 | 0.82 | PDE4B (0.33) | HCAR2ALDH1A1HSD17B10FBP1TSHR | |
| SCHEMBL287238 | 0.79 | ALDH1A1 (0.33) | HCAR2ALDH1A1HSD17B10FBP1TSHR | |
| SCHEMBL9297041 | 0.77 | HSD17B10 (0.38) | ALDH1A1HSD17B10TSHRHPGDMAPT | |
| SCHEMBL8308665 | 0.76 | ALDH1A1 (0.39) | HCAR2ALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL20718289 | 0.76 | ALDH1A1 (0.31) | HCAR2ALDH1A1HSD17B10FBP1TSHR | |
| SCHEMBL8516132 | 0.76 | IKBKB (0.40) | ALDH1A1HSD17B10HPGDKDM4EKMT2A | |
| SCHEMBL30295440 | 0.76 | ALDH1A1 (0.31) | HCAR2ALDH1A1HSD17B10FBP1TSHR | |
| SCHEMBL2632694 | 0.76 | MAPT (0.33) | HCAR2ALDH1A1HSD17B10FBP1TSHR | |
| SCHEMBL569207 | 0.75 | FBP1 (0.55) | ALDH1A1FBP1MAPTSMN1; SMN2PIN1 | |
| SCHEMBL1398803 | 0.73 | PTGS2 (0.50) | ALDH1A1HPGDSMN1; SMN2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017040-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC (US) | 2010-02-11 | — | — | WO | disclosed |