SCHEMBL3260752

SCHEMBL3260752

O=S(=O)(Nc1ccccc1O)c1ccc2ccccc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.62
KMT2A Q03164 7/20 0.62
GAA P10253 3/20 0.62
MAPT P10636 1/20 0.62
MAPK1 P28482 1/20 0.62
HTT P42858 1/20 0.62
RECQL P46063 1/20 0.62
DDX3X O00571 1/20 0.59
GLO1 Q04760 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
GFER P55789 1/20 0.59
PLAU P00749 1/20 0.58
PGAM1 P18669 2/20 0.58
UQCRB P14927 2/20 0.57
HSD17B2 P37059 1/20 0.57
ALDH1A1 P00352 2/20 0.57
POLB P06746 1/20 0.57
PKM P14618 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
KAT6A Q92794 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8658095 0.84 MEN1 (0.52) MEN1KMT2AGAAMAPTMAPK1
SCHEMBL28326534 0.84 HSD17B2 (0.61) MEN1KMT2AGAAMAPTPGAM1
SCHEMBL28326526 0.84 MEN1 (0.56) MEN1KMT2AGAAHTTGLO1
SCHEMBL9942107 0.84 HSD17B2 (0.61) MEN1KMT2AGAAMAPTPGAM1
SCHEMBL28878201 0.84 WDR5 (0.64) MEN1KMT2AGAAMAPTHTT
SCHEMBL7005529 0.83 MEN1 (0.52) MEN1KMT2AGAAGLO1TDP1
SCHEMBL3260612 0.82 HKDC1 (0.66) MEN1KMT2AGAAMAPTGFER
SCHEMBL16187949 0.81 KMT2A (0.60) MEN1KMT2AMAPTRECQLGLO1
SCHEMBL28327804 0.81 MEN1 (0.56) MEN1KMT2AGLO1TDP1PLAU
SCHEMBL9942077 0.81 RECQL (0.71) MEN1KMT2AMAPTHTTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110452183-A A kind of preparation method of chiral heterocycle compound SHANGHAI INST ORGANIC CHEMISTRY CAS 2019-11-15 CN disclosed
EP-2096149-B1 INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED MITSUBISHI PAPER MILLS LTD (JP) 2014-10-22 EP disclosed
US-8283285-B2 Scratch color-developable ink and invisible information printed sheet MITSUBISHI PAPER MILLS LIMITED (JP) 2012-10-09 US disclosed
US-20120148604-A1 TRP INHIBITORS AND USES THEREOF TRANSPOSAGEN BIOPHARMACEUTICALS, INC. (US) 2012-06-14 US disclosed
US-20120148604-A1 TRP INHIBITORS AND USES THEREOF TRANSPOSAGEN BIOPHARMACEUTICALS, INC. (US) 2012-06-14 US disclosed
US-20100021702-A1 SCRATCH COLOR-DEVELOPABLE INK AND INVISIBLE INFORMATION PRINTED SHEET MITSUBISHI PAPER INK MFG. CO., LTD. (JP) 2010-01-28 US disclosed
EP-2096149-A1 INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED Mitsubishi Paper Mills Limited (JP) 2009-09-02 EP disclosed
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120148604-A1 TRP INHIBITORS AND USES THEREOF TRPC4, TRPC1, TRPC3 MEN1 4622/4885KMT2A 2025/4885GAA 4467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.