Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.78 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.72 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.69 |
| ▸ | F3 | P13726 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | KRAS | P01116 | 1/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.63 |
| ▸ | XDH | P47989 | 2/20 | 0.62 |
| ▸ | P4HB | P07237 | 1/20 | 0.62 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260868 | 1.00 | TNFRSF1A (0.78) | TNFRSF1ATUBB1CXCL12ABCG2F3 | |
| SCHEMBL25185035 | 0.89 | TUBB1 (0.72) | TNFRSF1ATUBB1CXCL12ABCG2F3 | |
| SCHEMBL3219109 | 0.87 | TNFRSF1A (1.00) | TNFRSF1ACXCL12ABCG2F3MEN1 | |
| SCHEMBL3219103 | 0.87 | TNFRSF1A (1.00) | TNFRSF1ACXCL12ABCG2F3MEN1 | |
| SCHEMBL30383145 | 0.87 | LMNA (0.63) | TNFRSF1ATUBB1CXCL12ABCG2MEN1 | |
| SCHEMBL25191002 | 0.87 | LMNA (0.63) | TNFRSF1ATUBB1CXCL12ABCG2MEN1 | |
| SCHEMBL3738108 | 0.86 | CXCL12 (0.74) | TNFRSF1ATUBB1CXCL12ABCG2MEN1 | |
| SCHEMBL3263021 | 0.85 | TNFRSF1A (0.80) | TNFRSF1ACXCL12ABCG2F3MEN1 | |
| SCHEMBL3263018 | 0.85 | TNFRSF1A (0.80) | TNFRSF1ACXCL12ABCG2F3MEN1 | |
| SCHEMBL25195682 | 0.85 | CXCL12 (0.80) | TNFRSF1ATUBB1CXCL12ABCG2F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |