Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | RORA | P35398 | 1/20 | 0.64 |
| ▸ | RORC | P51449 | 1/20 | 0.64 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.63 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | TYMS | P04818 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20851111 | 0.90 | ALDH1A1 (0.59) | TSHRPGRRORARORCNR1H2 | |
| SCHEMBL812673 | 0.86 | TSHR (0.74) | TSHRPGRRORARORCNR1H2 | |
| SCHEMBL31110643 | 0.86 | TSHR (0.74) | TSHRPGRRORARORCNR1H2 | |
| SCHEMBL3259317 | 0.84 | ALDH1A1 (0.64) | TSHRPGRRORARORCNR1H2 | |
| SCHEMBL16785737 | 0.84 | TSHR (0.67) | TSHRPGRRORARORCNR1H2 | |
| SCHEMBL6409546 | 0.84 | TSHR (0.67) | TSHRPGRRORARORCNR1H2 | |
| SCHEMBL9478942 | 0.84 | TSHR (0.71) | TSHRPGRRORARORCNR1H2 | |
| SCHEMBL15762086 | 0.83 | TSHR (1.00) | TSHRPGRRORARORCNR1H2 | |
| SCHEMBL5046687 | 0.82 | TSHR (0.64) | TSHRPGRRORARORCNR1H2 | |
| SCHEMBL12793716 | 0.80 | ALDH1A1 (0.65) | TSHRPGRRORARORCNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462179-A4 | NOVEL SULFONAMIDES AS RADIOSENSITIZERS | — | 1992-03-18 | — | — | EP | claimed |
| EP-0462179-A1 | NOVEL SULFONAMIDES AS RADIOSENSITIZERS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-27 | — | — | EP | claimed |
| WO-1990009787-A1 | NOVEL SULFONAMIDES AS RADIOSENSITIZERS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1990-09-07 | — | — | WO | claimed |
| US-9834022-B2 | Thermal recording material | MITSUBISHI PAPER MILLS LIMITED (JP) | 2017-12-05 | — | — | US | disclosed |
| EP-3031611-B1 | THERMAL RECORDING MATERIAL | MITSUBISHI PAPER MILLS LTD (JP) | 2017-09-27 | — | — | EP | disclosed |
| US-20160332469-A1 | THERMAL RECORDING MATERIAL | MITSUBISHI PAPER MILLS LIMITED (JP) | 2016-11-17 | — | — | US | disclosed |
| EP-3031611-A1 | THERMAL RECORDING MATERIAL | Mitsubishi Paper Mills Limited (JP) | 2016-06-15 | — | — | EP | disclosed |
| EP-2096149-B1 | INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED | MITSUBISHI PAPER MILLS LTD (JP) | 2014-10-22 | — | — | EP | disclosed |
| US-8288313-B2 | Thermal recording material | MITSUBISHI PAPER MILLS LIMITED (JP) | 2012-10-16 | — | — | US | disclosed |
| US-8283285-B2 | Scratch color-developable ink and invisible information printed sheet | MITSUBISHI PAPER MILLS LIMITED (JP) | 2012-10-09 | — | — | US | disclosed |
| US-20100069240-A1 | THERMAL RECORDING MATERIAL | MITSUBISHI PAPER MILLS LIMITED (JP) | 2010-03-18 | — | — | US | disclosed |
| EP-2096149-A1 | INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED | Mitsubishi Paper Mills Limited (JP) | 2009-09-02 | — | — | EP | disclosed |
| US-20070026259-A1 | Thermal recording material | MITSUBISHI PAPER MILLS LIMITED (JP) | 2007-02-01 | — | — | US | disclosed |
| EP-1245561-B1 | N-SUBSTITUTED BENZYL OR PHENYL AROMATIC SULFAMIDES COMPOUNDS AND THE USE THEREOF | SHANGHAI INST MATERIA MEDICA (CN) | 2005-12-28 | — | — | EP | disclosed |
| US-6921740-B1 | Electron-receiving compound and thermal recording material | MITSUBISHI PAPER MIILS LTD. (JP) | 2005-07-26 | — | — | US | disclosed |
| US-6605635-B1 | Prevention and treatment of cardiac arrhythmia; condensation of aromatic sulfochloride with p-hydroxybenzylamine followed by mannich reaction | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCE (CN) | 2003-08-12 | — | — | US | disclosed |
| EP-1245561-A1 | N-SUBSTITUTED BENZYL OR PHENYL AROMATIC SULFAMIDES COMPOUNDS AND THE USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2002-10-02 | — | — | EP | disclosed |
| EP-0462179-A4 | NOVEL SULFONAMIDES AS RADIOSENSITIZERS | — | 1992-03-18 | — | — | EP | disclosed |
| EP-0462179-A1 | NOVEL SULFONAMIDES AS RADIOSENSITIZERS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-27 | — | — | EP | disclosed |
| WO-1990009787-A1 | NOVEL SULFONAMIDES AS RADIOSENSITIZERS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1990-09-07 | — | — | WO | disclosed |