Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261286 | 1.00 | F2 (0.46) | F2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3261637 | 0.91 | ALDH1A1 (0.38) | F2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3261635 | 0.91 | ALDH1A1 (0.38) | F2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3262208 | 0.87 | F2 (0.46) | F2ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL3262209 | 0.87 | F2 (0.46) | F2ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL3261290 | 0.83 | F2 (0.48) | F2 | |
| SCHEMBL3260257 | 0.79 | F2 (0.39) | F2SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL3260256 | 0.79 | F2 (0.39) | F2SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL3261109 | 0.75 | AURKA (0.50) | ALDH1A1MAPT | |
| SCHEMBL3261111 | 0.75 | AURKA (0.50) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011147-A1 | INDOLE COMPOUNDS | THIA MEDICA AS (NO) | 2010-01-28 | — | — | WO | disclosed |