Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262208 | 1.00 | F2 (0.46) | F2FFAR1GABRA1GABRG2GABRB3 | |
| SCHEMBL3260257 | 0.91 | F2 (0.39) | F2FFAR1NPC1GAAMAPT | |
| SCHEMBL3260256 | 0.91 | F2 (0.39) | F2FFAR1NPC1GAAMAPT | |
| SCHEMBL3261283 | 0.87 | F2 (0.46) | F2GABRA1GABRA3NPC1GAA | |
| SCHEMBL3261286 | 0.87 | F2 (0.46) | F2GABRA1GABRA3NPC1GAA | |
| SCHEMBL3261637 | 0.78 | ALDH1A1 (0.38) | F2FFAR1GABRA1GABRG2GABRB3 | |
| SCHEMBL3261635 | 0.78 | ALDH1A1 (0.38) | F2FFAR1GABRA1GABRG2GABRB3 | |
| SCHEMBL3261290 | 0.77 | F2 (0.48) | F2FFAR1CYP2C9BACE1 | |
| SCHEMBL3259934 | 0.76 | CYP2A6 (0.46) | NPC1MAPTRAB9AALDH1A1BACE1 | |
| SCHEMBL3259931 | 0.76 | CYP2A6 (0.46) | NPC1MAPTRAB9AALDH1A1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011147-A1 | INDOLE COMPOUNDS | THIA MEDICA AS (NO) | 2010-01-28 | — | — | WO | disclosed |