Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260257 | 1.00 | F2 (0.39) | F2NPC1GAAMAPTXBP1 | |
| SCHEMBL3262209 | 0.91 | F2 (0.46) | F2NPC1GAAMAPTXBP1 | |
| SCHEMBL3262208 | 0.91 | F2 (0.46) | F2NPC1GAAMAPTXBP1 | |
| SCHEMBL3261637 | 0.88 | ALDH1A1 (0.38) | F2NPC1GAAMAPTRAB9A | |
| SCHEMBL3261635 | 0.88 | ALDH1A1 (0.38) | F2NPC1GAAMAPTRAB9A | |
| SCHEMBL3261643 | 0.79 | TBXAS1 (0.42) | F2FFAR1TBXA2RPTGER4PTGFR | |
| SCHEMBL3261286 | 0.79 | F2 (0.46) | F2NPC1GAAMAPTRAB9A | |
| SCHEMBL3261283 | 0.79 | F2 (0.46) | F2NPC1GAAMAPTRAB9A | |
| SCHEMBL3261904 | 0.77 | PPARG (0.45) | F2FFAR1CTNNB1PPARG | |
| SCHEMBL3262489 | 0.75 | RAB9A (0.48) | F2RAB9AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011147-A1 | INDOLE COMPOUNDS | THIA MEDICA AS (NO) | 2010-01-28 | — | — | WO | disclosed |