Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.51 |
| ▸ | LPL | P06858 | 12/20 | 0.51 |
| ▸ | F11 | P03951 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076177 | 0.86 | LPL (0.53) | LIPGLPLF11ESR2CA1 | |
| SCHEMBL520826 | 0.80 | LPL (0.61) | LIPGLPLF11ESR2CA1 | |
| Hydrochloric Acid SCHEMBL2594775 | 0.79 | LPL (0.59) | LIPGLPLF11ESR2CA1 | |
| SCHEMBL307558 | 0.78 | SIGMAR1 (0.49) | LIPGLPLF11ESR2 | |
| SCHEMBL20584964 | 0.78 | LIPG (0.57) | LIPGLPLF11ESR2F2 | |
| SCHEMBL6225307 | 0.77 | LIPG (0.71) | LIPGLPLF11ESR2F2 | |
| SCHEMBL1684669 | 0.77 | LIPG (0.53) | LIPGLPLF11ESR2F2 | |
| SCHEMBL1285032 | 0.77 | LIPG (0.65) | LIPGLPLF11ESR2F2 | |
| SCHEMBL14696602 | 0.76 | LIPG (0.47) | LIPGLPLF11ESR2CA1 | |
| SCHEMBL14659461 | 0.76 | LIPG (0.51) | LIPGLPLF11ESR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010184-A1 | [1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |