Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | GPR17 | Q13304 | 3/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.36 |
| ▸ | APOL1 | O14791 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636076 | 0.82 | KDM4E (0.55) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL3638375 | 0.79 | CYP1A2 (0.45) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL3232286 | 0.78 | SMN1; SMN2 (0.55) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL3379855 | 0.78 | MAP2 (0.47) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL3263047 | 0.78 | MAPT (0.39) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL3639386 | 0.77 | CYP1A2 (0.57) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL3264986 | 0.76 | MAPT (0.75) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL3261013 | 0.75 | SIRT1 (0.39) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL3639755 | 0.74 | CYP1A2 (0.41) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL3382868 | 0.73 | KDM4E (0.55) | KDM4EGAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012396-A1 | 5,6 SUBSTITUTED BENZAMIDE DERIVATIVES AS MODULATORS OF THE EP<SB>2 </SB>RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | WO | claimed |
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | disclosed |