Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | APOL1 | O14791 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263047 | 0.85 | MAPT (0.39) | KDM4EMEN1GAAMAPTKMT2A | |
| SCHEMBL3261013 | 0.83 | SIRT1 (0.39) | SIRT1KDM4EMEN1GAAMAPT | |
| SCHEMBL3264690 | 0.81 | AKR1C2 (0.47) | KDM4EMEN1GAAMAPTKMT2A | |
| SCHEMBL3382968 | 0.81 | ICMT (0.38) | MAP2KDM4EMEN1GAAMAPT | |
| SCHEMBL3382173 | 0.80 | SIRT1 (0.38) | SIRT1KDM4EMEN1GAAMAPT | |
| SCHEMBL3228500 | 0.79 | KRAS (0.51) | MAP2APOL1KRAS | |
| SCHEMBL3636076 | 0.78 | KDM4E (0.55) | KDM4EMEN1GAAMAPTKMT2A | |
| SCHEMBL3261669 | 0.78 | KDM4E (0.44) | SIRT1KDM4EMEN1GAAMAPT | |
| SCHEMBL3639755 | 0.76 | CYP1A2 (0.41) | SIRT1KDM4EMEN1GAAMAPT | |
| SCHEMBL3638375 | 0.75 | CYP1A2 (0.45) | SIRT1KDM4EMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |