Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113595 | 0.78 | HTR2A (0.39) | HTR2AHTR2CSLC6A4PTGS2KDM4E | |
| SCHEMBL27689316 | 0.78 | PTGS2 (0.45) | HTR2AHTR2CSLC6A4PTGS2KDM4E | |
| SCHEMBL5120984 | 0.77 | SMN1; SMN2 (0.46) | HTR2AHTR2CSLC6A4POLBMEN1 | |
| SCHEMBL3265521 | 0.76 | POLB (0.45) | PTGS2KDM4EPOLBMEN1CYP1A2 | |
| SCHEMBL3322508 | 0.75 | LMNA (0.61) | PTGS2KDM4EPOLBCYP2C19SMN1; SMN2 | |
| SCHEMBL3262792 | 0.73 | MAPK1 (0.53) | KDM4EPOLBCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL1374365 | 0.72 | POLB (0.73) | PTGS2KDM4EPOLBMEN1CYP1A2 | |
| SCHEMBL12402397 | 0.72 | PTGS2 (0.48) | PTGS2KDM4EPOLBMEN1KMT2A | |
| SCHEMBL17673290 | 0.72 | PTGS2 (0.48) | PTGS2KDM4EPOLBMEN1KMT2A | |
| SCHEMBL13991168 | 0.72 | PTGS2 (0.42) | PTGS2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217640-A1 | POLYURETHANE FOAM CONTAINING SILICON | Wacker Chemie AG (DE) | 2010-08-18 | — | — | EP | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| WO-2009071510-A1 | POLYURETHANE FOAM CONTAINING SILICON | WACKER CHEMIE AG (DE) | 2009-06-11 | — | — | WO | disclosed |
| EP-1996638-A2 | FOAMS CONTAINING SILICON | Wacker Chemie AG (DE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107435-A2 | SILICONE CONTAINING FOAMS | WACKER CHEMIE AG (DE) | 2007-09-27 | — | — | WO | disclosed |
| EP-0362318-B1 | 2,3-DIFLUOROBIPHENYLS | MERCK PATENT GmbH (DE) | 1993-08-04 | — | — | EP | disclosed |