Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111923 | 0.84 | HTR2A (0.60) | SMN1; SMN2CYP1A2ALDH1A1HPGDGAA | |
| SCHEMBL1739414 | 0.81 | AURKA (0.38) | ALDH1A1HPGDTSHRMEN1KMT2A | |
| SCHEMBL28113595 | 0.81 | HTR2A (0.39) | SMN1; SMN2MALT1GAAP2RY14POLB | |
| SCHEMBL20488594 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP1A2MALT1MEN1KMT2A | |
| SCHEMBL22054628 | 0.80 | GAA (0.59) | SMN1; SMN2CYP1A2ALDH1A1HPGDMEN1 | |
| SCHEMBL3202480 | 0.80 | PPARG (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL24423881 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP1A2MALT1ALDH1A1HPGD | |
| SCHEMBL28339416 | 0.79 | GRN (0.59) | SMN1; SMN2CYP1A2MALT1MEN1KMT2A | |
| SCHEMBL15056504 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP1A2MALT1ALDH1A1MEN1 | |
| SCHEMBL5106653 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP1A2ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | SMN1; SMN2 3876/4885CYP1A2 655/4885MALT1 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.