SCHEMBL3262148

SCHEMBL3262148

CO[SiH](OC)OCCCCC(C)C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
RARB P10826 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2498333 0.98 LMNA (0.37) LMNARARB
SCHEMBL29144606 0.86 LMNA (0.42) LMNARARB
SCHEMBL3260320 0.83 ALDH1A1 (0.37)
SCHEMBL984977 0.78 LMNA (0.36) LMNARARB
SCHEMBL9722067 0.78 LMNA (0.36) LMNARARB
SCHEMBL6065961 0.73 THRB (0.35)
SCHEMBL9634314 0.72
SCHEMBL6561619 0.71 THRB (0.40)
SCHEMBL18429940 0.71 ALDH1A1 (0.32)
SCHEMBL3150640 0.71 HDAC3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2782951-B1 LOW CHLORIDE COMPOSITIONS OF OLEFINICALLY FUNCTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2019-01-02 EP claimed
EP-2782953-B1 COMPOSITION OF OLEFINICALLY FUNCTIONALSIED SILOXANE OLIGOMERS BASED ON ALKOXY SILANES EVONIK DEGUSSA GMBH (DE) 2018-07-25 EP claimed
EP-2782952-B1 MIXTURES, PARTICULARLY LOW IN VOLATILE ORGANIC COMPOUNDS (VOC), OF OLEFINICALLY FUNTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXY SILANES EVONIK DEGUSSA GMBH (DE) 2015-09-09 EP claimed
EP-1358946-B1 Process for impregnating porous inorganic substrates EVONIK DEGUSSA GMBH (DE) 2010-03-03 EP claimed