SCHEMBL3262791

SCHEMBL3262791

CC1(C)OB(c2ccc(CN3CC[C@@H](O)C3)cc2)OC1(C)C

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
LTA4H P09960 7/20 0.46
LPL P06858 5/20 0.46
LIPG Q9Y5X9 5/20 0.46
F11 P03951 1/20 0.44
MEN1 O00255 1/20 0.41
CYP2D6 P10635 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
MCHR1 Q99705 1/20 0.39
ESR2 Q92731 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3261628 1.00 ALDH1A1 (0.46) ALDH1A1LTA4HLPLLIPGF11
SCHEMBL3261633 1.00 ALDH1A1 (0.46) ALDH1A1LTA4HLPLLIPGF11
SCHEMBL18580223 0.92 ALDH1A1 (0.57) ALDH1A1LTA4HLPLLIPGF11
SCHEMBL18579804 0.92 ALDH1A1 (0.49) ALDH1A1LTA4HLPLLIPGF11
SCHEMBL18580578 0.89 LPL (0.50) LPLLIPGF11ESR2
SCHEMBL3263221 0.85 LPL (0.47) LTA4HLPLLIPGF11ESR2
SCHEMBL3264388 0.85 LPL (0.47) LTA4HLPLLIPGF11ESR2
SCHEMBL3263222 0.85 LPL (0.47) LTA4HLPLLIPGF11ESR2
SCHEMBL18580257 0.84 LPL (0.46) LTA4HLPLLIPGF11ESR2
SCHEMBL3260869 0.82 LPL (0.49) LTA4HLPLLIPGF11ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12195446-B2 Heteroaryl compounds and their use as therapeutic drugs DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2025-01-14 US disclosed
US-20230002353-A1 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS DONG A SOCIO HOLDINGS CO LTD (KR) 2023-01-05 US disclosed
US-10947215-B2 Heteroaryl compounds and their use as therapeutic drugs DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2021-03-16 US disclosed
EP-3344613-B1 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS DONG A SOCIO HOLDINGS CO LTD (KR) 2020-03-04 EP disclosed
US-20190119252-A1 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2019-04-25 US disclosed
US-10125118-B2 Heteroaryl compounds and their use as therapeutic drugs DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2018-11-13 US disclosed
EP-3344613-A1 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS Dong-A Socio Holdings Co., Ltd. (KR) 2018-07-11 EP disclosed
US-20170355690-A9 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2017-12-14 US disclosed
US-20170066742-A1 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS DONG-A SOCIO HOLDINGS CO LTD (KR) 2017-03-09 US disclosed
WO-2017039331-A1 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2017-03-09 WO disclosed
WO-2010010184-A1 [1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS GALAPAGOS NV (BE) 2010-01-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170355690-A9 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS MERTK, ERBB2, SRC ALDH1A1 3115/4885LTA4H 4113/4885LPL 3708/4885
US-10947215-B2 Heteroaryl compounds and their use as therapeutic drugs MERTK, ERBB2, SRC ALDH1A1 3115/4885LTA4H 4113/4885LPL 3708/4885
US-12195446-B2 Heteroaryl compounds and their use as therapeutic drugs MERTK, ERBB2, SRC ALDH1A1 3115/4885LTA4H 4113/4885LPL 3708/4885
US-10125118-B2 Heteroaryl compounds and their use as therapeutic drugs MERTK, ERBB2, SRC ALDH1A1 3115/4885LTA4H 4113/4885LPL 3708/4885
US-20190119252-A1 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS MERTK, ERBB2, SRC ALDH1A1 3115/4885LTA4H 4113/4885LPL 3708/4885
US-20230002353-A1 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS MERTK, ERBB2, SRC ALDH1A1 3115/4885LTA4H 4113/4885LPL 3708/4885
US-20170066742-A1 HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS MERTK, ERBB2, SRC ALDH1A1 3115/4885LTA4H 4113/4885LPL 3708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.