SCHEMBL3263022

SCHEMBL3263022

C=C(CC(=O)C=O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TET2 Q6N021 5/20 0.36
TET3 O43151 1/20 0.36
TET1 Q8NFU7 1/20 0.36
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
GRM1 Q13255 1/20 0.34
GRM2 Q14416 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1127575 0.79 ALOX15 (0.62) ALOX15HSD17B10TET2TET3TET1
SCHEMBL9627004 0.77 ALOX15 (0.38) ALOX15HSD17B10TET2TET3TET1
SCHEMBL1809603 0.76 ALOX15 (0.57) ALOX15HSD17B10TET2TET3TET1
SCHEMBL5308018 0.76
SCHEMBL1082038 0.75 ALOX15 (0.52) ALOX15HSD17B10TET2TET3TET1
Itaconate SCHEMBL9319413 0.74 ALOX15 (0.70) ALOX15HSD17B10TET2TET3TET1
SCHEMBL28089517 0.72 HAO1 (0.45)
Itaconate SCHEMBL286967 0.71 ALOX15 (0.75) ALOX15HSD17B10TET2TET3TET1
SCHEMBL822245 0.71
Itaconate SCHEMBL21523 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100022024-A1 Method for testing performance of reagents containing microparticles OLYMPUS CORPORATION (JP) 2010-01-28 US disclosed
EP-2048502-A1 METHOD OF CONFIRMING THE SPECIMEN-DETECTING ACTIVITY OF MICROPARTICLES Olympus Corporation (JP) 2009-04-15 EP disclosed