SCHEMBL9627004

SCHEMBL9627004

C=C(CCC(=O)C=O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TET2 Q6N021 5/20 0.34
TET3 O43151 1/20 0.34
TET1 Q8NFU7 1/20 0.34
GRIK1 P39086 1/20 0.33
GRIK2 Q13002 1/20 0.33
GRM1 Q13255 1/20 0.33
GRM2 Q14416 1/20 0.33
TBXAS1 P24557 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL273086 0.81 TET2 (0.46) ALOX15HSD17B10TET2TET3TET1
SCHEMBL17315005 0.80 ALOX15 (0.48) ALOX15HSD17B10TET2TET3TET1
SCHEMBL3263022 0.77 ALOX15 (0.50) ALOX15HSD17B10TET2TET3TET1
SCHEMBL7086929 0.73
SCHEMBL10663570 0.73 LMNA (0.56) ALOX15HSD17B10TET2TET3TET1
SCHEMBL304951 0.73 TET2 (0.40) ALOX15HSD17B10TET2TET3TET1
SCHEMBL26631 0.73 LMNA (0.56) ALOX15HSD17B10TET2TET3TET1
SCHEMBL1821741 0.72
Ammonia Solution, Strong SCHEMBL18315389 0.70 LMNA (0.53) ALOX15HSD17B10TET2TET3TET1
SCHEMBL20262536 0.70 LMNA (0.53) ALOX15HSD17B10TET2TET3TET1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0190495-B1 POLYMER GEL AND USE THEREOF FOR SEPARATING COMPONENTS FROM LIQUID RESULTING FROM DESULFURIZATION AND DECYANIZATION PROCESS JAPAN EXLAN COMPANY, LTD. (JP) 1992-04-01 EP claimed
US-4737290-A CROSSLINKED POLYMER WITH 2,3-DIHYDROXYPROPYL (METH)ACRYLATE OR (METH)ALLYL ETHER UNITS; THIOCYANATES JAPAN EXLAN COMPANY, LIMITED (JP) 1988-04-12 US disclosed