Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434374 | 0.80 | ALDH1A1 (0.36) | CYP1A2CYP2D6 | |
| SCHEMBL5823784 | 0.80 | MAOB (0.52) | CYP1A2 | |
| SCHEMBL2050612 | 0.77 | — | — | |
| SCHEMBL30269693 | 0.77 | CHRNB2 (0.55) | CHRNB2CHRNA4CYP1A2CYP2D6CHRNA7 | |
| SCHEMBL1582780 | 0.77 | CHRNB2 (0.55) | CHRNB2CHRNA4CYP1A2CYP2D6CHRNA7 | |
| SCHEMBL16397911 | 0.77 | CHRNB2 (0.55) | CHRNB2CHRNA4CYP1A2CYP2D6CHRNA7 | |
| SCHEMBL6158142 | 0.74 | CYP1A2 (0.48) | CHRNB2CHRNA4CYP1A2CYP2D6CHRNA7 | |
| SCHEMBL16606321 | 0.73 | CHRNB2 (0.56) | CHRNB2CHRNA4CYP1A2CYP2D6CHRNA7 | |
| SCHEMBL15654716 | 0.72 | CYP1A2 (0.40) | CHRNB2CHRNA4CYP1A2CYP2D6CHRNA7 | |
| SCHEMBL19792803 | 0.71 | CHRNB2 (0.67) | CHRNB2CHRNA4CYP1A2CYP2D6CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014022-A1 | A PROCESS FOR THE PREPARATION OF IMATINIB | TEMAPHARM SP. Z O.O. (PL) | 2010-02-04 | — | — | WO | disclosed |