Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264074 | 0.86 | KMT2A (0.53) | ALOX5NR4A2KDM4EHSD17B10MAPK1 | |
| SCHEMBL3264046 | 0.86 | KDM4E (0.47) | ALOX5NR4A2KDM4EHSD17B10MAPK1 | |
| SCHEMBL3265812 | 0.83 | KMT2A (0.43) | ALOX5KDM4EHSD17B10MAPK1MEN1 | |
| SCHEMBL3261338 | 0.82 | NR4A2 (0.56) | ALOX5NR4A2KDM4EHSD17B10MEN1 | |
| SCHEMBL7428961 | 0.80 | NR4A2 (0.57) | ALOX5NR4A2KDM4EHSD17B10MEN1 | |
| SCHEMBL3151973 | 0.80 | NR4A2 (0.59) | ALOX5NR4A2KDM4EHSD17B10MEN1 | |
| SCHEMBL9317997 | 0.80 | NR4A2 (0.69) | ALOX5NR4A2KDM4EHSD17B10MEN1 | |
| SCHEMBL3263240 | 0.80 | NR4A2 (0.53) | ALOX5NR4A2KDM4EHSD17B10MEN1 | |
| SCHEMBL3263959 | 0.78 | NR4A2 (0.51) | ALOX5NR4A2KDM4EHSD17B10MEN1 | |
| SCHEMBL8810246 | 0.76 | NR4A2 (0.63) | ALOX5NR4A2KDM4EHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008727-A1 | ASYMMETRIC SYNTHESIS OF ALLYL OR ALLENE OXINDOLES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-01-21 | — | — | WO | disclosed |