Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263245 | 0.86 | ALOX5 (0.60) | KMT2AMEN1POLBAPOBEC3ACASP6 | |
| SCHEMBL3265812 | 0.85 | KMT2A (0.43) | KMT2AMEN1POLBAPOBEC3ACASP6 | |
| SCHEMBL3264046 | 0.83 | KDM4E (0.47) | KMT2AMEN1POLBAPOBEC3ACASP6 | |
| SCHEMBL3263777 | 0.78 | KDM4E (0.51) | KMT2AMEN1KDM4ETDP1ALOX5 | |
| SCHEMBL4625769 | 0.78 | KDM4E (0.51) | KMT2AKDM4ETDP1MAPTAPP | |
| SCHEMBL7311543 | 0.76 | KDM4E (0.57) | KMT2AMEN1KDM4ETDP1ALOX5 | |
| SCHEMBL10478444 | 0.76 | KDM4E (0.53) | KMT2AMEN1POLBAPOBEC3ACASP6 | |
| SCHEMBL7459854 | 0.75 | KDM4E (0.58) | KMT2AMEN1KDM4ETDP1ALOX5 | |
| SCHEMBL3426478 | 0.70 | KDM4E (0.66) | KMT2AMEN1KDM4ETDP1MAPT | |
| SCHEMBL23664064 | 0.69 | KDM4E (0.61) | KMT2AMEN1KDM4ETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008727-A1 | ASYMMETRIC SYNTHESIS OF ALLYL OR ALLENE OXINDOLES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-01-21 | — | — | WO | disclosed |