Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263245 | 0.86 | ALOX5 (0.60) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL3264074 | 0.83 | KMT2A (0.53) | KDM4EHSD17B10ALDH1A1MAPK1ALOX5 | |
| SCHEMBL3265812 | 0.80 | KMT2A (0.43) | KDM4EHSD17B10ALDH1A1MAPK1ALOX5 | |
| SCHEMBL28243565 | 0.73 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1HPGDALOX5 | |
| SCHEMBL31486047 | 0.69 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL3261338 | 0.68 | NR4A2 (0.56) | KDM4EHSD17B10ALDH1A1HPGDALOX5 | |
| SCHEMBL8181582 | 0.68 | MAPT (0.54) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL8173489 | 0.68 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1HPGDALOX5 | |
| SCHEMBL7428961 | 0.67 | NR4A2 (0.57) | KDM4EHSD17B10ALDH1A1HPGDALOX5 | |
| SCHEMBL3151973 | 0.67 | NR4A2 (0.59) | KDM4EHSD17B10ALDH1A1HPGDALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008727-A1 | ASYMMETRIC SYNTHESIS OF ALLYL OR ALLENE OXINDOLES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-01-21 | — | — | WO | disclosed |